Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 8896..9572 Replicon plasmid bgla_3p
Accession NC_015378
Organism Burkholderia gladioli BSR3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BGLA_RS36305 Protein ID WP_044275898.1
Coordinates 8896..9327 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F2LSB7
Locus tag BGLA_RS36310 Protein ID WP_013691848.1
Coordinates 9351..9572 (-) Length 74 a.a.

Genomic Context

BGLA_RS40805BGLA_RS36290BGLA_RS36315BGLA_RS36280BGLA_RS36285BGLA_RS36295BGLA_RS36300BGLA_RS36305BGLA_RS36310BGLA_RS36320BGLA_RS42240BGLA_RS36325BGLA_RS36330BGLA_RS36335BGLA_RS39035
Location: 6285..6536 (252 bp)
Type: Others
Protein ID: WP_013691843.1
Location: 6546..7376 (831 bp)
Type: Others
Protein ID: WP_013691844.1
Location: 9764..10234 (471 bp)
Type: Others
Protein ID: WP_044275836.1
Location: 4007..5239 (1233 bp)
Type: Others
Protein ID: WP_013691841.1
Location: 5339..5983 (645 bp)
Type: Others
Protein ID: WP_013691842.1
Location: 7502..7696 (195 bp)
Type: Others
Protein ID: WP_013691845.1
Location: 7788..8873 (1086 bp)
Type: Others
Protein ID: WP_013691846.1
Location: 8896..9327 (432 bp)
Type: Toxin
Protein ID: WP_044275898.1
Location: 9351..9572 (222 bp)
Type: Antitoxin
Protein ID: WP_013691848.1
Location: 10389..10595 (207 bp)
Type: Others
Protein ID: WP_148270701.1
Location: 10623..10973 (351 bp)
Type: Others
Protein ID: WP_148270703.1
Location: 10988..11593 (606 bp)
Type: Others
Protein ID: WP_013691849.1
Location: 11608..11901 (294 bp)
Type: Others
Protein ID: WP_044275838.1
Location: 12181..12906 (726 bp)
Type: Others
Protein ID: WP_013691850.1
Location: 12979..14109 (1131 bp)
Type: Others
Protein ID: WP_013691851.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BGLA_RS362804007..5239-1233WP_013691841.1tyrosine-type recombinase/integrase-
BGLA_RS362855339..5983-645WP_013691842.1hypothetical protein-
BGLA_RS408056285..6536+252WP_013691843.1hypothetical protein-
BGLA_RS362906546..7376+831WP_013691844.1hypothetical protein-
BGLA_RS362957502..7696-195WP_013691845.1hypothetical protein-
BGLA_RS363007788..8873-1086WP_013691846.1hypothetical protein-
BGLA_RS363058896..9327-432WP_044275898.1PIN domain-containing proteinToxin
BGLA_RS363109351..9572-222WP_013691848.1hypothetical proteinAntitoxin
BGLA_RS363159764..10234+471WP_044275836.1hypothetical protein-
BGLA_RS3632010389..10595-207WP_148270701.1hypothetical protein-
BGLA_RS4224010623..10973-351WP_148270703.1hypothetical protein-
BGLA_RS3632510988..11593-606WP_013691849.1hypothetical protein-
BGLA_RS3633011608..11901-294WP_044275838.1hypothetical protein-
BGLA_RS3633512181..12906-726WP_013691850.1parR-
BGLA_RS3903512979..14109-1131WP_013691851.1ParB/RepB/Spo0J family partition protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..128650128650


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15614.80 Da        Isoelectric Point: 6.0490

>T25178 WP_044275898.1 NC_015378:c9327-8896 [Burkholderia gladioli BSR3]
MTYLLDVNVLIALLDAGHVQHEAAHEWFGSAAHAAWATCPLTENGVLRIIGNPRYPNTLGTPAAVAPLVTQLRAHPGHTF
WWDDLSLLNPEQVDVSRILATDQVTDTYLLALARVHGGKLATFDRRLVVDAVPDGARHLEIIS

Download         Length: 432 bp

>T25178 NC_015378:c9327-8896 [Burkholderia gladioli BSR3]
ATGACTTACCTGCTCGACGTCAACGTCCTGATCGCGCTGCTCGATGCGGGCCACGTGCAGCACGAGGCGGCGCACGAATG
GTTTGGCAGCGCCGCGCACGCGGCGTGGGCGACCTGCCCGCTGACCGAAAACGGCGTGCTGCGCATCATCGGCAACCCGC
GCTACCCGAACACGCTGGGCACGCCCGCCGCGGTCGCGCCGCTCGTCACACAGCTGCGCGCGCACCCGGGGCACACGTTC
TGGTGGGACGACCTGAGCCTGCTCAATCCGGAACAGGTCGACGTGAGCCGCATCCTCGCCACCGACCAGGTGACCGACAC
CTACCTGCTCGCGCTCGCGCGCGTGCACGGGGGCAAGCTGGCCACCTTCGACCGACGCCTCGTGGTCGATGCGGTGCCCG
ACGGCGCGCGCCATCTCGAAATCATCAGCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 7851.97 Da        Isoelectric Point: 7.0108

>AT25178 WP_013691848.1 NC_015378:c9572-9351 [Burkholderia gladioli BSR3]
MRTTLEIDDDVLALARARADREHVSIGRIISQLARAALQPAAAAPTTRNGLPVLPSARTVTPELVNQLRDEAP

Download         Length: 222 bp

>AT25178 NC_015378:c9572-9351 [Burkholderia gladioli BSR3]
ATGCGCACCACCCTCGAAATCGACGACGACGTACTGGCGCTCGCTCGCGCGCGCGCCGACCGCGAGCACGTCTCGATCGG
CCGCATCATCTCGCAGCTCGCGCGCGCCGCGCTGCAGCCGGCGGCCGCGGCACCCACCACCCGCAACGGCCTGCCCGTGC
TGCCGAGCGCGCGCACGGTCACGCCCGAGCTCGTCAACCAGCTTCGCGACGAGGCGCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBF2LSB7

References