Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1420476..1422319 Replicon chromosome
Accession NC_015376
Organism Burkholderia gladioli BSR3

Toxin (Protein)


Gene name doc Uniprot ID F2LLA2
Locus tag BGLA_RS25105 Protein ID WP_013689907.1
Coordinates 1420476..1421441 (+) Length 322 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag BGLA_RS25110 Protein ID WP_044275309.1
Coordinates 1421459..1422319 (+) Length 287 a.a.

Genomic Context

BGLA_RS25080BGLA_RS25085BGLA_RS25090BGLA_RS25095BGLA_RS25100BGLA_RS25105BGLA_RS25110BGLA_RS25115BGLA_RS25120BGLA_RS25125BGLA_RS25130BGLA_RS25075
Location: 1417278..1417595 (318 bp)
Type: Others
Protein ID: WP_013689902.1
Location: 1417598..1417909 (312 bp)
Type: Others
Protein ID: WP_013689903.1
Location: 1417951..1419060 (1110 bp)
Type: Others
Protein ID: WP_013689904.1
Location: 1419053..1419823 (771 bp)
Type: Others
Protein ID: WP_013689905.1
Location: 1419922..1420449 (528 bp)
Type: Others
Protein ID: WP_013689906.1
Location: 1420476..1421441 (966 bp)
Type: Toxin
Protein ID: WP_013689907.1
Location: 1421459..1422319 (861 bp)
Type: Antitoxin
Protein ID: WP_044275309.1
Location: 1422316..1423113 (798 bp)
Type: Others
Protein ID: WP_013689909.1
Location: 1423106..1424779 (1674 bp)
Type: Others
Protein ID: WP_013689910.1
Location: 1424772..1425605 (834 bp)
Type: Others
Protein ID: WP_013689911.1
Location: 1425682..1427172 (1491 bp)
Type: Others
Protein ID: WP_013689912.1
Location: 1415785..1416864 (1080 bp)
Type: Others
Protein ID: WP_013689901.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BGLA_RS250751415785..1416864-1080WP_013689901.1porin-
BGLA_RS250801417278..1417595+318WP_013689902.1non-heme iron oxygenase ferredoxin subunit-
BGLA_RS250851417598..1417909+312WP_013689903.1hypothetical protein-
BGLA_RS250901417951..1419060+1110WP_013689904.1aromatic ring-hydroxylating dioxygenase subunit alpha-
BGLA_RS250951419053..1419823+771WP_013689905.1SDR family oxidoreductase-
BGLA_RS251001419922..1420449+528WP_013689906.1cupin domain-containing protein-
BGLA_RS251051420476..1421441+966WP_013689907.1alpha/beta fold hydrolaseToxin
BGLA_RS251101421459..1422319+861WP_044275309.1IclR family transcriptional regulatorAntitoxin
BGLA_RS251151422316..1423113+798WP_013689909.1SDR family oxidoreductase-
BGLA_RS251201423106..1424779+1674WP_013689910.1thiamine pyrophosphate-binding protein-
BGLA_RS251251424772..1425605+834WP_013689911.1aspartate dehydrogenase-
BGLA_RS251301425682..1427172+1491WP_013689912.1aldehyde dehydrogenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(66-305)

Antitoxin

Transcription regulator IclR, N-terminal

(25-73)


Sequences

Toxin        


Download         Length: 322 a.a.        Molecular weight: 32764.23 Da        Isoelectric Point: 6.7497

>T25175 WP_013689907.1 NC_015376:1420476-1421441 [Burkholderia gladioli BSR3]
MSEIDPRGAEAEAGPDAALAARLGQFPARRIAIREAGLIGWRESGPVEGAGDSTARAAAGERALPVVLLHGIGSGAASWL
AQLDTLGASRRVLAWDAPGYGESTPVAPASPLAADYAAALAGWLDALAIERCVLVGHSLGAIVAGAFARRHAGRLAGLLL
VSPAAGYGAAPAATRDERRDARLAMLAALGPAGLAEQRSANMLSAHAGEAARAWVRRVMAQVKPAGYTQATHLLANADLA
ADLAAWRATTDAAGAARVEVMVGAEDGITPPNACERIAAAAGVALRIVPRAGHAGYVEAPERYSELIGAFCARCDESWRL
A

Download         Length: 966 bp

>T25175 NC_015376:1420476-1421441 [Burkholderia gladioli BSR3]
ATGAGCGAAATCGATCCGCGCGGGGCCGAGGCAGAGGCCGGGCCCGACGCGGCCCTGGCCGCCCGGCTCGGGCAGTTTCC
GGCGCGGCGCATCGCCATTCGCGAAGCCGGGCTGATCGGCTGGCGCGAATCGGGTCCAGTTGAGGGGGCCGGCGATTCGA
CGGCACGCGCGGCCGCTGGCGAGCGGGCATTGCCGGTGGTGCTGCTGCACGGCATCGGCTCGGGCGCGGCCTCGTGGCTG
GCCCAGCTCGACACGCTCGGCGCGTCGCGTCGCGTGCTGGCCTGGGACGCGCCCGGTTATGGCGAATCGACGCCGGTCGC
GCCGGCCTCGCCGCTGGCGGCCGATTACGCGGCGGCGCTGGCCGGCTGGCTCGACGCGCTCGCCATCGAGCGCTGCGTGC
TGGTGGGGCACTCGCTCGGCGCGATCGTGGCCGGCGCCTTCGCGCGCCGGCATGCCGGGCGGCTGGCCGGCTTGCTGCTG
GTTTCGCCGGCCGCCGGCTACGGCGCGGCGCCGGCCGCCACGCGCGACGAACGGCGCGATGCGCGGCTCGCGATGCTGGC
CGCGCTCGGGCCCGCGGGCCTGGCCGAACAACGCAGTGCCAACATGCTGTCGGCGCATGCCGGCGAGGCCGCCCGCGCCT
GGGTGCGCCGCGTGATGGCGCAGGTGAAGCCGGCCGGTTACACGCAGGCCACCCACCTGCTCGCGAACGCCGACCTGGCC
GCCGATCTCGCCGCCTGGCGGGCGACGACCGACGCCGCCGGTGCCGCGCGCGTGGAGGTGATGGTGGGCGCCGAGGACGG
CATCACGCCGCCGAACGCCTGCGAACGGATCGCGGCGGCGGCCGGCGTGGCGCTGCGCATCGTGCCGCGCGCCGGCCATG
CCGGCTACGTGGAGGCACCCGAGCGCTACTCAGAGCTGATCGGCGCGTTCTGCGCGCGCTGCGACGAATCATGGAGACTG
GCATGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31049.35 Da        Isoelectric Point: 6.5132

>AT25175 WP_044275309.1 NC_015376:1421459-1422319 [Burkholderia gladioli BSR3]
MRSEPADSGAPEADAANGAYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNY
RLGVAVLRLGFEYLSSLELTDLGLPVIEGLREATGFTTHIVIRDGRDVVFVAKAQSAAPAFSSIRVNVGTRLPAHATTHG
HVLMGDLSEAELRALYPERQLERATRATPDSLEALLALVREDAARGYGISNSSFERGISVVTAPVRNDTQRIVAAVTVTV
PKPEIDAALIADGLVEKVVRAANELSRRLNYRSDDENSYLKALGLR

Download         Length: 861 bp

>AT25175 NC_015376:1421459-1422319 [Burkholderia gladioli BSR3]
CTGCGAAGCGAGCCGGCCGACAGCGGCGCGCCCGAGGCGGATGCCGCGAACGGCGCCTACGTGGTACCTGGCCTCGAACG
CGGGCTGCGGATCCTCGCGGAATTCTCGCCGCGCGAGCCGGTGCTGGGCGCGCCGGAATTGTCGAAGCGGCTCGGCATTC
CGCGCACCACGGTGTTCCGGCTGCTGCAGACGCTCGAATCGCTGGGCTTCCTGGAGCGCGCCGACAAGGACCGCAATTAC
CGGCTCGGCGTGGCGGTGCTGCGCCTGGGCTTCGAATACTTGAGCTCGCTGGAGCTGACCGACCTGGGCCTGCCGGTGAT
CGAGGGCCTGCGCGAGGCGACCGGCTTCACCACCCATATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCCAAGG
CGCAGAGCGCGGCGCCGGCCTTCAGCTCGATTCGCGTCAACGTCGGCACGCGGCTGCCCGCGCATGCCACCACCCACGGC
CACGTGCTGATGGGCGACCTGAGCGAGGCCGAGCTGCGCGCGCTGTACCCCGAGCGCCAGCTCGAACGCGCCACGCGCGC
CACGCCCGACAGCCTGGAGGCGCTGCTCGCGCTGGTCCGCGAGGATGCCGCGCGCGGCTACGGCATCAGCAACTCCTCGT
TCGAGCGCGGCATCTCGGTGGTCACCGCGCCGGTGCGCAACGACACGCAGCGCATCGTGGCGGCCGTCACGGTGACGGTG
CCGAAACCCGAGATCGACGCGGCGCTGATCGCCGACGGCCTGGTCGAGAAGGTCGTGAGGGCGGCCAATGAACTGTCGCG
GCGGCTCAATTACCGCTCCGATGATGAGAACTCCTATCTGAAGGCATTGGGATTGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBF2LLA2

Antitoxin

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Source
ID
Structure
No matching records found

References