Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2042290..2042561 Replicon chromosome
Accession NZ_CP101269
Organism Escherichia coli strain EC21Z-048

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2042420..2042523 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2042290..2042561 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NML18_RS09930 2038845..2039507 - 663 WP_000944256.1 exodeoxyribonuclease X -
NML18_RS09935 2039531..2040187 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NML18_RS09940 2040289..2040519 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NML18_RS09945 2040658..2041032 + 375 WP_000204699.1 CopC domain-containing protein YobA -
NML18_RS09950 2041036..2041908 + 873 WP_254837425.1 copper homeostasis membrane protein CopD -
NML18_RS09955 2041921..2042262 + 342 WP_000976472.1 YebY family protein -
- 2042290..2042561 - 272 - - Antitoxin
- 2042420..2042523 + 104 - - Toxin
NML18_RS09960 2042658..2043314 + 657 WP_000812710.1 protein-serine/threonine phosphatase -
NML18_RS09965 2043315..2043506 - 192 WP_001296140.1 YebW family protein -
NML18_RS09970 2043611..2043847 - 237 WP_001295499.1 YebV family protein -
NML18_RS09975 2043965..2045404 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T251734 NZ_CP101269:2042420-2042523 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT251734 NZ_CP101269:c2042561-2042290 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References