Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2706076..2706347 Replicon chromosome
Accession NZ_CP101222
Organism Escherichia coli strain EC21Z-144

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2706114..2706217 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2706076..2706347 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NML25_RS13005 2703233..2704672 + 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NML25_RS13010 2704790..2705026 + 237 WP_001295499.1 YebV family protein -
NML25_RS13015 2705131..2705322 + 192 WP_001296140.1 YebW family protein -
NML25_RS13020 2705323..2705979 - 657 WP_001551231.1 protein-serine/threonine phosphatase -
- 2706076..2706347 + 272 - - Antitoxin
- 2706114..2706217 - 104 - - Toxin
NML25_RS13025 2706375..2706716 - 342 WP_000976472.1 YebY family protein -
NML25_RS13030 2706729..2707601 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NML25_RS13035 2707605..2707979 - 375 WP_000168747.1 CopC domain-containing protein YobA -
NML25_RS13040 2708118..2708348 + 231 WP_000916763.1 DNA polymerase III subunit theta -
NML25_RS13045 2708450..2709106 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
NML25_RS13050 2709130..2709792 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2703227..2713657 10430
- inside Prophage - - 2705323..2714480 9157


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T251553 NZ_CP101222:c2706217-2706114 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT251553 NZ_CP101222:2706076-2706347 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References