Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2221636..2221907 Replicon chromosome
Accession NZ_CP101197
Organism Escherichia coli strain EC21Z-151

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2221766..2221869 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2221636..2221907 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NML27_RS10615 2218191..2218853 - 663 WP_000944256.1 exodeoxyribonuclease X -
NML27_RS10620 2218877..2219533 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
NML27_RS10625 2219635..2219865 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NML27_RS10630 2220004..2220378 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NML27_RS10635 2220382..2221254 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NML27_RS10640 2221267..2221608 + 342 WP_000976472.1 YebY family protein -
- 2221636..2221907 - 272 - - Antitoxin
- 2221766..2221869 + 104 - - Toxin
NML27_RS10645 2222004..2222660 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
NML27_RS10650 2222661..2222852 - 192 WP_001296140.1 YebW family protein -
NML27_RS10655 2222957..2223193 - 237 WP_001295499.1 YebV family protein -
NML27_RS10660 2223311..2224750 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2214326..2237747 23421
- inside Prophage - - 2184331..2237747 53416


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T251477 NZ_CP101197:2221766-2221869 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT251477 NZ_CP101197:c2221907-2221636 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References