Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4074846..4075408 Replicon chromosome
Accession NZ_CP101185
Organism Paenarthrobacter ureafaciens strain SD-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NL394_RS19200 Protein ID WP_021472908.1
Coordinates 4075118..4075408 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7M2BYL4
Locus tag NL394_RS19195 Protein ID WP_021472907.1
Coordinates 4074846..4075121 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL394_RS19175 (NL394_19130) 4071069..4072106 - 1038 WP_031216691.1 zinc-dependent alcohol dehydrogenase family protein -
NL394_RS19180 (NL394_19135) 4072236..4073048 - 813 WP_021472904.1 hypothetical protein -
NL394_RS19185 (NL394_19140) 4073095..4073736 - 642 WP_021472905.1 LysE family translocator -
NL394_RS19190 (NL394_19145) 4073935..4074813 + 879 WP_043427191.1 prephenate dehydratase -
NL394_RS19195 (NL394_19150) 4074846..4075121 + 276 WP_021472907.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NL394_RS19200 (NL394_19155) 4075118..4075408 + 291 WP_021472908.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NL394_RS19205 (NL394_19160) 4075420..4076397 - 978 WP_021472909.1 thioredoxin-disulfide reductase -
NL394_RS19210 (NL394_19165) 4076461..4078632 - 2172 WP_069696782.1 MMPL family transporter -
NL394_RS19215 (NL394_19170) 4078795..4079430 + 636 WP_259362707.1 MarR family transcriptional regulator -
NL394_RS19220 (NL394_19175) 4079511..4080326 + 816 WP_021474094.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10888.46 Da        Isoelectric Point: 10.0347

>T251469 WP_021472908.1 NZ_CP101185:4075118-4075408 [Paenarthrobacter ureafaciens]
VSNSSLEGEPWNIQVTSPALKTFHRLPEKAASAIVEFITGALAGNPHRLSKPLTNELLGMRTARRGDYRVLFTLDIEDHV
LYVHRIQHRADVYKPR

Download         Length: 291 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10112.30 Da        Isoelectric Point: 4.6847

>AT251469 WP_021472907.1 NZ_CP101185:4074846-4075121 [Paenarthrobacter ureafaciens]
MKTVPLSEAKDKLSALVEEADTTHEIIQITRHGHPSAVLMSADDLESLQETIHWLSQPGLREDLAQARRDIAEGNTVSGD
DLRREFGLPPR

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7M2BYL4

References