Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1273050..1273828 Replicon chromosome
Accession NZ_CP101178
Organism Xanthomonas campestris pv. campestris strain CN13

Toxin (Protein)


Gene name TacT2 Uniprot ID Q8P667
Locus tag XCCCN13v2_RS05385 Protein ID WP_011038220.1
Coordinates 1273050..1273541 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID Q8P668
Locus tag XCCCN13v2_RS05390 Protein ID WP_011038219.1
Coordinates 1273538..1273828 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCCCN13v2_RS05370 1269378..1270253 + 876 WP_011038222.1 30S ribosomal protein S6--L-glutamate ligase -
XCCCN13v2_RS05375 1270903..1271580 + 678 WP_003490678.1 response regulator transcription factor -
XCCCN13v2_RS05380 1271573..1272907 + 1335 WP_019237347.1 HAMP domain-containing sensor histidine kinase -
XCCCN13v2_RS05385 1273050..1273541 - 492 WP_011038220.1 GNAT family N-acetyltransferase Toxin
XCCCN13v2_RS05390 1273538..1273828 - 291 WP_011038219.1 DUF1778 domain-containing protein Antitoxin
XCCCN13v2_RS05395 1273903..1274304 - 402 WP_019237348.1 SymE family type I addiction module toxin -
XCCCN13v2_RS05400 1274836..1275459 - 624 WP_011038217.1 dephospho-CoA kinase -
XCCCN13v2_RS05405 1275473..1276336 - 864 WP_011038216.1 A24 family peptidase -
XCCCN13v2_RS05410 1276343..1277599 - 1257 WP_011038215.1 type II secretion system F family protein -
XCCCN13v2_RS05415 1277926..1278366 + 441 WP_011038214.1 pilin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17638.31 Da        Isoelectric Point: 8.1192

>T251466 WP_011038220.1 NZ_CP101178:c1273541-1273050 [Xanthomonas campestris pv. campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10678.23 Da        Isoelectric Point: 10.5480

>AT251466 WP_011038219.1 NZ_CP101178:c1273828-1273538 [Xanthomonas campestris pv. campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q8P667

Antitoxin

Source ID Structure
AlphaFold DB Q8P668

References