Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3782984..3783762 Replicon chromosome
Accession NZ_CP101169
Organism Xanthomonas campestris pv. campestris strain CN02

Toxin (Protein)


Gene name TacT2 Uniprot ID Q8P667
Locus tag XCCCN02v2_RS16940 Protein ID WP_011038220.1
Coordinates 3783271..3783762 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID Q8P668
Locus tag XCCCN02v2_RS16935 Protein ID WP_011038219.1
Coordinates 3782984..3783274 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCCCN02v2_RS16910 3778010..3779266 + 1257 WP_075285409.1 type II secretion system F family protein -
XCCCN02v2_RS16915 3779272..3780135 + 864 WP_075285408.1 A24 family peptidase -
XCCCN02v2_RS16920 3780149..3780772 + 624 WP_075285407.1 dephospho-CoA kinase -
XCCCN02v2_RS16930 3782508..3782909 + 402 WP_040940795.1 SymE family type I addiction module toxin -
XCCCN02v2_RS16935 3782984..3783274 + 291 WP_011038219.1 DUF1778 domain-containing protein Antitoxin
XCCCN02v2_RS16940 3783271..3783762 + 492 WP_011038220.1 GNAT family N-acetyltransferase Toxin
XCCCN02v2_RS16945 3783905..3785239 - 1335 WP_162808569.1 HAMP domain-containing sensor histidine kinase -
XCCCN02v2_RS16950 3785232..3785909 - 678 WP_003490678.1 response regulator transcription factor -
XCCCN02v2_RS16955 3786559..3787434 - 876 WP_016945000.1 30S ribosomal protein S6--L-glutamate ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17638.31 Da        Isoelectric Point: 8.1192

>T251457 WP_011038220.1 NZ_CP101169:3783271-3783762 [Xanthomonas campestris pv. campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10678.23 Da        Isoelectric Point: 10.5480

>AT251457 WP_011038219.1 NZ_CP101169:3782984-3783274 [Xanthomonas campestris pv. campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q8P667

Antitoxin

Source ID Structure
AlphaFold DB Q8P668

References