251449

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 607740..608659 Replicon chromosome
Accession NZ_CP101130
Organism Bacillus sp. KRF7

Toxin (Protein)


Gene name spoIISA Uniprot ID M5PDF4
Locus tag NL113_RS02840 Protein ID WP_006638546.1
Coordinates 607740..608486 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID A0A7Y8RVI2
Locus tag NL113_RS02845 Protein ID WP_029418621.1
Coordinates 608486..608659 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL113_RS02825 603911..605671 - 1761 WP_006638543.1 gamma-glutamyltransferase -
NL113_RS02830 605999..606616 + 618 WP_006638544.1 DUF47 domain-containing protein -
NL113_RS02835 606629..607627 + 999 WP_006638545.1 inorganic phosphate transporter -
NL113_RS02840 607740..608486 + 747 WP_006638546.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
NL113_RS02845 608486..608659 + 174 WP_029418621.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
NL113_RS02850 608959..610227 - 1269 WP_006638548.1 MFS transporter -
NL113_RS02855 610255..611271 - 1017 WP_006638549.1 zinc-binding alcohol dehydrogenase family protein -
NL113_RS02860 611291..612139 - 849 WP_006638550.1 SDR family oxidoreductase -
NL113_RS02865 612115..613212 - 1098 WP_006638551.1 mannonate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29647.11 Da        Isoelectric Point: 4.6172

>T251449 WP_006638546.1 NZ_CP101130:607740-608486 [Bacillus sp. KRF7]
MLLFYQFSVWVIVLALALYVFAVWRFEKKMKEKTIAIRKTWYLLYVIGAVIYWTYNPQSLFTDPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSNELATDTRELLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGDIEAYAEGIEKLIKRFAEKMNISASL
CEYNSEQSKDHLLEHMENRFAVQEKLERKDVYYEENGKMVLIPFSIHEYDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PYEEEGDE

Download         Length: 747 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6961.93 Da        Isoelectric Point: 10.7390

>AT251449 WP_029418621.1 NZ_CP101130:608486-608659 [Bacillus sp. KRF7]
MEPVFQHDEDRSIKRGAWKVFKKQSRTNIAKYELSPHTERIFRQNARLIDEYKRKNA

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M5PDF4

Antitoxin

Source ID Structure
AlphaFold DB A0A7Y8RVI2

References