Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 7051368..7051899 Replicon chromosome
Accession NZ_CP101125
Organism Pseudomonas nunensis strain In5

Toxin (Protein)


Gene name relE Uniprot ID A0A6L5BQB4
Locus tag NK667_RS31220 Protein ID WP_054616769.1
Coordinates 7051368..7051670 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6L5BNJ0
Locus tag NK667_RS31225 Protein ID WP_054616768.1
Coordinates 7051660..7051899 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NK667_RS31205 (NK667_31205) 7047571..7049190 + 1620 WP_054616772.1 DUF2300 domain-containing protein -
NK667_RS31210 (NK667_31210) 7049194..7050003 + 810 WP_054616771.1 DUF2135 domain-containing protein -
NK667_RS31215 (NK667_31215) 7050174..7051286 + 1113 WP_054616770.1 endonuclease NucS -
NK667_RS31220 (NK667_31220) 7051368..7051670 - 303 WP_054616769.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NK667_RS31225 (NK667_31225) 7051660..7051899 - 240 WP_054616768.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NK667_RS31230 (NK667_31230) 7052162..7052800 - 639 WP_054616767.1 retron Ec78 anti-phage system effector HNH endonuclease PtuB -
NK667_RS31235 (NK667_31235) 7052802..7054259 - 1458 WP_054616766.1 AAA family ATPase -
NK667_RS31240 (NK667_31240) 7054770..7055621 - 852 WP_054616765.1 hypothetical protein -
NK667_RS31245 (NK667_31245) 7055943..7056143 + 201 WP_054616764.1 AlpA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11827.60 Da        Isoelectric Point: 9.7094

>T251448 WP_054616769.1 NZ_CP101125:c7051670-7051368 [Pseudomonas nunensis]
MTYSLEFDRRALKEWNKLGDTLRQQFKKKLAEVLENPRIEANRLRQLPDCYKLKLRSAGYRLIYQVLDQEVVVFVVAIGK
REREAAYQDAQERIGQQPAD

Download         Length: 303 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8837.19 Da        Isoelectric Point: 4.6017

>AT251448 WP_054616768.1 NZ_CP101125:c7051899-7051660 [Pseudomonas nunensis]
MASINIRIDDDLKQRSFAELEKLGVTPSELLRQTLQYVAERGKLPFKAALLSEEDEALIAVVTERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6L5BQB4

Antitoxin

Source ID Structure
AlphaFold DB A0A6L5BNJ0

References