Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-couple_hipB |
Location | 6333057..6334657 | Replicon | chromosome |
Accession | NZ_CP101125 | ||
Organism | Pseudomonas nunensis strain In5 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | NK667_RS27830 | Protein ID | WP_054617082.1 |
Coordinates | 6333057..6334382 (+) | Length | 442 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | NK667_RS27835 | Protein ID | WP_054048289.1 |
Coordinates | 6334379..6334657 (+) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NK667_RS27825 (NK667_27825) | 6329867..6332824 | - | 2958 | WP_054617083.1 | autotransporter domain-containing protein | - |
NK667_RS27830 (NK667_27830) | 6333057..6334382 | + | 1326 | WP_054617082.1 | HipA domain-containing protein | Toxin |
NK667_RS27835 (NK667_27835) | 6334379..6334657 | + | 279 | WP_054048289.1 | helix-turn-helix transcriptional regulator | Antitoxin |
NK667_RS27840 (NK667_27840) | 6334744..6335580 | - | 837 | WP_054048291.1 | amino acid ABC transporter permease | - |
NK667_RS27845 (NK667_27845) | 6335577..6336398 | - | 822 | WP_054048293.1 | ABC transporter substrate-binding protein | - |
NK667_RS27850 (NK667_27850) | 6336511..6337410 | + | 900 | WP_054617081.1 | homocysteine S-methyltransferase family protein | - |
NK667_RS27855 (NK667_27855) | 6337531..6338202 | - | 672 | WP_054617080.1 | GNAT family protein | - |
NK667_RS27860 (NK667_27860) | 6338221..6338667 | - | 447 | WP_054617079.1 | GNAT family N-acetyltransferase | - |
NK667_RS27865 (NK667_27865) | 6338677..6339300 | - | 624 | WP_054617078.1 | FMN-binding negative transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 442 a.a. Molecular weight: 48946.71 Da Isoelectric Point: 4.9693
>T251446 WP_054617082.1 NZ_CP101125:6333057-6334382 [Pseudomonas nunensis]
MYTLTLQVYTSGNWLDAMTLVFTEPEKGFEGPCRFGYKKDYVATNLEYIDSQFSKAVSARLPLDWDNTSLKKAPAFLLDI
APAGAAKRFLMARVGQDKPEGISADLFLLGRSTPAPIGHMRIKESAEAADDRPAVGFRREEVVARDNTFLEYAYEQGAAI
GGATGAGGEAPKLLMSQGRDGLLYPDAVLSDDQVVQHWFVKFARNRAAQTDQIILKSEFHYYKALHVLGIETIAEDGLAL
EEATKPSLWMKRFDREVTDQGVERLAVESIYSLAGVTVPGSYMNHLEVIQLLARLWKQAGQVDQVPALVSDYLRRDLLNK
ILGNSDNHGRNTSIIRGTDSFRLAPIYDLAPMVMDDEGVTRTTKWPKDLEVAGEVKWREVCDALADIEDPEALFEGLRTD
ANRLLALPDILTASGLPEATMNHPGVALRNLEQRLKTWGLK
MYTLTLQVYTSGNWLDAMTLVFTEPEKGFEGPCRFGYKKDYVATNLEYIDSQFSKAVSARLPLDWDNTSLKKAPAFLLDI
APAGAAKRFLMARVGQDKPEGISADLFLLGRSTPAPIGHMRIKESAEAADDRPAVGFRREEVVARDNTFLEYAYEQGAAI
GGATGAGGEAPKLLMSQGRDGLLYPDAVLSDDQVVQHWFVKFARNRAAQTDQIILKSEFHYYKALHVLGIETIAEDGLAL
EEATKPSLWMKRFDREVTDQGVERLAVESIYSLAGVTVPGSYMNHLEVIQLLARLWKQAGQVDQVPALVSDYLRRDLLNK
ILGNSDNHGRNTSIIRGTDSFRLAPIYDLAPMVMDDEGVTRTTKWPKDLEVAGEVKWREVCDALADIEDPEALFEGLRTD
ANRLLALPDILTASGLPEATMNHPGVALRNLEQRLKTWGLK
Download Length: 1326 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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