Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3049885..3050404 Replicon chromosome
Accession NZ_CP101125
Organism Pseudomonas nunensis strain In5

Toxin (Protein)


Gene name relE Uniprot ID A0A6L5C1Y7
Locus tag NK667_RS13035 Protein ID WP_054615008.1
Coordinates 3049885..3050166 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NK667_RS13040 Protein ID WP_054615009.1
Coordinates 3050156..3050404 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NK667_RS13005 (NK667_13005) 3045080..3045844 - 765 WP_054615004.1 IclR family transcriptional regulator -
NK667_RS13010 (NK667_13010) 3045991..3046380 - 390 WP_054615005.1 RidA family protein -
NK667_RS13015 (NK667_13015) 3046417..3047208 - 792 WP_054615006.1 amino acid ABC transporter ATP-binding protein -
NK667_RS13020 (NK667_13020) 3047205..3047867 - 663 WP_054046640.1 amino acid ABC transporter permease -
NK667_RS13025 (NK667_13025) 3047877..3048539 - 663 WP_054046642.1 amino acid ABC transporter permease -
NK667_RS13030 (NK667_13030) 3048717..3049565 - 849 WP_054615007.1 transporter substrate-binding domain-containing protein -
NK667_RS13035 (NK667_13035) 3049885..3050166 - 282 WP_054615008.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NK667_RS13040 (NK667_13040) 3050156..3050404 - 249 WP_054615009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NK667_RS13045 (NK667_13045) 3050714..3051145 + 432 WP_054615010.1 thioredoxin family protein -
NK667_RS13050 (NK667_13050) 3051288..3052847 - 1560 WP_054615011.1 TerC family protein -
NK667_RS13055 (NK667_13055) 3053232..3054098 - 867 WP_054615012.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10880.66 Da        Isoelectric Point: 10.4586

>T251442 WP_054615008.1 NZ_CP101125:c3050166-3049885 [Pseudomonas nunensis]
MTYELEFSEKAWKEWKKLGVNLREQFKNKLQERLVHPHVPADRLHGLGNAYKIKLRSAGYRLVYRVKDEVLIVTVIAVGK
RERGGVYKDAGER

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8935.37 Da        Isoelectric Point: 4.5338

>AT251442 WP_054615009.1 NZ_CP101125:c3050404-3050156 [Pseudomonas nunensis]
MTHIVLSQVVASISELKKNPMGTVAAGGGLSVAILNRNEPAFYCVPAKEYEAMMSRLEDLELIALCKERENDPTVKVSID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6L5C1Y7

Antitoxin

Source ID Structure

References