Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 178933..179438 Replicon chromosome
Accession NZ_CP101125
Organism Pseudomonas nunensis strain In5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NK667_RS00865 Protein ID WP_054613585.1
Coordinates 178933..179187 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NK667_RS00870 Protein ID WP_054613586.1
Coordinates 179184..179438 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NK667_RS00835 (NK667_00835) 174021..174728 + 708 WP_054045475.1 peptide-methionine (S)-S-oxide reductase MsrA -
NK667_RS00840 (NK667_00840) 174723..175205 - 483 WP_054613581.1 GNAT family N-acetyltransferase -
NK667_RS00845 (NK667_00845) 175251..175655 - 405 WP_054045471.1 GNAT family N-acetyltransferase -
NK667_RS00850 (NK667_00850) 175652..176665 - 1014 WP_054613582.1 sensor domain-containing diguanylate cyclase -
NK667_RS00855 (NK667_00855) 176741..177646 - 906 WP_054613583.1 LysR family transcriptional regulator -
NK667_RS00860 (NK667_00860) 177749..178924 + 1176 WP_054613584.1 aspartate aminotransferase family protein -
NK667_RS00865 (NK667_00865) 178933..179187 - 255 WP_054613585.1 Txe/YoeB family addiction module toxin Toxin
NK667_RS00870 (NK667_00870) 179184..179438 - 255 WP_054613586.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NK667_RS00875 (NK667_00875) 179637..180221 - 585 WP_054613587.1 DedA family protein -
NK667_RS00880 (NK667_00880) 180206..180637 - 432 WP_054613588.1 VOC family protein -
NK667_RS00885 (NK667_00885) 180651..181151 - 501 WP_054613589.1 adenylate kinase -
NK667_RS00890 (NK667_00890) 181312..183213 - 1902 WP_054613590.1 alkaline phosphatase D family protein -
NK667_RS00895 (NK667_00895) 183274..183525 - 252 WP_054613591.1 hypothetical protein -
NK667_RS00900 (NK667_00900) 183515..184306 - 792 WP_054613592.1 VacJ family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9945.42 Da        Isoelectric Point: 8.0137

>T251441 WP_054613585.1 NZ_CP101125:c179187-178933 [Pseudomonas nunensis]
MNIEFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQREPFSGPGKPEPLKYNLSGFWSRRITAEHRLVYAIEDGAIQIVMC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9500.94 Da        Isoelectric Point: 9.6212

>AT251441 WP_054613586.1 NZ_CP101125:c179438-179184 [Pseudomonas nunensis]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGNLRAGKTKARR
LIEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References