251414

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1436..2021 Replicon plasmid unnamed1
Accession NZ_CP101116
Organism Acinetobacter sp. Z1

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag NGC85_RS16920 Protein ID WP_254805640.1
Coordinates 1734..2021 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag NGC85_RS16915 Protein ID WP_254805639.1
Coordinates 1436..1747 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGC85_RS16905 (NGC85_16905) 701..916 - 216 WP_004652785.1 30S ribosomal protein S21 -
NGC85_RS16910 (NGC85_16910) 1057..1362 - 306 WP_254805638.1 hypothetical protein -
NGC85_RS16915 (NGC85_16915) 1436..1747 - 312 WP_254805639.1 BrnA antitoxin family protein Antitoxin
NGC85_RS16920 (NGC85_16920) 1734..2021 - 288 WP_254805640.1 BrnT family toxin Toxin
NGC85_RS16925 (NGC85_16925) 2428..3057 + 630 WP_254805641.1 hypothetical protein -
NGC85_RS16930 (NGC85_16930) 3926..4141 + 216 WP_254805642.1 hypothetical protein -
NGC85_RS16935 (NGC85_16935) 4854..5777 + 924 WP_254805643.1 replication initiation protein RepM -
NGC85_RS16940 (NGC85_16940) 5838..6398 + 561 WP_254805632.1 plasmid replication DNA-binding protein -
NGC85_RS16945 (NGC85_16945) 6594..6956 - 363 WP_254805633.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..10205 10205


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11223.64 Da        Isoelectric Point: 4.7692

>T251414 WP_254805640.1 NZ_CP101116:c2021-1734 [Acinetobacter sp. Z1]
MELYFEWDEAKNQKNQKKHDVSFETASLIFEDPLRISIQDRHTDGEERWQSIGMVKGVLMLLVAHTIFDEDDCEIIRIIS
ARQVTKAERDKYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12083.74 Da        Isoelectric Point: 9.4651

>AT251414 WP_254805639.1 NZ_CP101116:c1747-1436 [Acinetobacter sp. Z1]
MSMVRYTRKELNDNFSDKQDAEIKRLLAKGTTPDEQLDLSDIPEITDWSHAVRHGQFYRPVKQQTSVRLDADVLAWLKEQ
GKGYQTRINKILREAMLKDLKNH

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References