Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4268654..4269323 Replicon chromosome
Accession NZ_CP100765
Organism Serratia nematodiphila strain SASK3000

Toxin (Protein)


Gene name cptA Uniprot ID A0A0P0QIF8
Locus tag NLX84_RS20290 Protein ID WP_033632171.1
Coordinates 4268654..4269076 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag NLX84_RS20295 Protein ID WP_004931679.1
Coordinates 4269057..4269323 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX84_RS20270 (NLX84_20270) 4264546..4265064 + 519 WP_004931683.1 flavodoxin FldB -
NLX84_RS20275 (NLX84_20275) 4265099..4266463 - 1365 WP_060560181.1 cell envelope integrity protein CreD -
NLX84_RS20280 (NLX84_20280) 4266544..4267962 - 1419 WP_033632173.1 two-component system sensor histidine kinase CreC -
NLX84_RS20285 (NLX84_20285) 4267959..4268654 - 696 WP_254734336.1 two-component system response regulator CreB -
NLX84_RS20290 (NLX84_20290) 4268654..4269076 - 423 WP_033632171.1 protein YgfX Toxin
NLX84_RS20295 (NLX84_20295) 4269057..4269323 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
NLX84_RS20300 (NLX84_20300) 4269645..4270637 + 993 WP_033632169.1 tRNA-modifying protein YgfZ -
NLX84_RS20305 (NLX84_20305) 4270676..4271173 - 498 WP_004931675.1 DUF2165 domain-containing protein -
NLX84_RS20310 (NLX84_20310) 4271324..4271998 - 675 WP_033632168.1 hemolysin III family protein -
NLX84_RS20315 (NLX84_20315) 4272182..4272790 + 609 WP_033632167.1 HD domain-containing protein -
NLX84_RS20320 (NLX84_20320) 4272831..4273757 - 927 WP_015378971.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16518.60 Da        Isoelectric Point: 10.8114

>T251403 WP_033632171.1 NZ_CP100765:c4269076-4268654 [Serratia nematodiphila]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGDGEES

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT251403 WP_004931679.1 NZ_CP100765:c4269323-4269057 [Serratia nematodiphila]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P0QIF8

Antitoxin

Source ID Structure

References