Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 460674..461245 Replicon chromosome
Accession NZ_CP100765
Organism Serratia nematodiphila strain SASK3000

Toxin (Protein)


Gene name relE Uniprot ID A0A086G7I6
Locus tag NLX84_RS02145 Protein ID WP_033631648.1
Coordinates 460970..461245 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A086G7I5
Locus tag NLX84_RS02140 Protein ID WP_013811307.1
Coordinates 460674..460961 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX84_RS02115 (NLX84_02115) 456443..457528 - 1086 WP_135637732.1 carbon-phosphorus lyase complex subunit PhnI -
NLX84_RS02120 (NLX84_02120) 457528..458109 - 582 WP_135637733.1 phosphonate C-P lyase system protein PhnH -
NLX84_RS02125 (NLX84_02125) 458113..458556 - 444 WP_033631646.1 phosphonate C-P lyase system protein PhnG -
NLX84_RS02130 (NLX84_02130) 458557..459285 - 729 WP_254734482.1 phosphonate metabolism transcriptional regulator PhnF -
NLX84_RS02135 (NLX84_02135) 459513..460568 + 1056 WP_135637734.1 permease -
NLX84_RS02140 (NLX84_02140) 460674..460961 + 288 WP_013811307.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NLX84_RS02145 (NLX84_02145) 460970..461245 + 276 WP_033631648.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
NLX84_RS02150 (NLX84_02150) 461251..461715 - 465 WP_033631649.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NLX84_RS02155 (NLX84_02155) 461884..464022 - 2139 WP_033631650.1 anaerobic ribonucleoside-triphosphate reductase -
NLX84_RS02160 (NLX84_02160) 464267..465181 - 915 WP_033631651.1 LysR family transcriptional regulator -
NLX84_RS02165 (NLX84_02165) 465287..465811 + 525 WP_033631652.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10723.48 Da        Isoelectric Point: 8.4940

>T251390 WP_033631648.1 NZ_CP100765:460970-461245 [Serratia nematodiphila]
MRIEWDNAALRDRERIFEFLYIFNPQAAVQADNEIDKAVKRLLDHPELGKPWYGKARKLLVDKASLLLVYIIVDDVIKVF
SIAHQREKFPN

Download         Length: 276 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11032.33 Da        Isoelectric Point: 5.8001

>AT251390 WP_013811307.1 NZ_CP100765:460674-460961 [Serratia nematodiphila]
MESRIQFRIEDETKRLAQKAAEAKGTTLSEACRRLAEQMADEQRAAEEHENWLKDKVDAAFSRLHEGNAVYLSQQEVEES
MDAFKAKIRAKYDRK

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086G7I6

Antitoxin

Source ID Structure
AlphaFold DB A0A086G7I5

References