Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 55775..56310 Replicon chromosome
Accession NZ_CP100765
Organism Serratia nematodiphila strain SASK3000

Toxin (Protein)


Gene name relE Uniprot ID A0A086G6D5
Locus tag NLX84_RS00250 Protein ID WP_033631416.1
Coordinates 56035..56310 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A086G6D4
Locus tag NLX84_RS00245 Protein ID WP_033631415.1
Coordinates 55775..56035 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX84_RS00225 (NLX84_00225) 51098..51748 + 651 WP_060558038.1 DcrB-related protein -
NLX84_RS00230 (NLX84_00230) 51784..52390 + 607 Protein_45 glutathione S-transferase -
NLX84_RS00235 (NLX84_00235) 52460..53854 + 1395 WP_135637687.1 L-seryl-tRNA(Sec) selenium transferase -
NLX84_RS00240 (NLX84_00240) 53851..55692 + 1842 WP_082997386.1 selenocysteine-specific translation elongation factor -
NLX84_RS00245 (NLX84_00245) 55775..56035 + 261 WP_033631415.1 ribbon-helix-helix domain-containing protein Antitoxin
NLX84_RS00250 (NLX84_00250) 56035..56310 + 276 WP_033631416.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLX84_RS00255 (NLX84_00255) 56322..57233 - 912 WP_135637688.1 LysR family transcriptional regulator -
NLX84_RS00260 (NLX84_00260) 57355..57981 + 627 WP_033631418.1 LysE family translocator -
NLX84_RS00265 (NLX84_00265) 58035..59282 - 1248 WP_033633516.1 MFS transporter -
NLX84_RS00270 (NLX84_00270) 59500..60492 + 993 WP_135637689.1 acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10548.30 Da        Isoelectric Point: 10.3377

>T251389 WP_033631416.1 NZ_CP100765:56035-56310 [Serratia nematodiphila]
MELKWTSKALSDLARLFEFLALANRTAAANSVKALVAAPKALLDNPRLGERLDEFLPQEVRRILVGRYEIRYQVQPAAIY
VLRIWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9712.03 Da        Isoelectric Point: 4.5317

>AT251389 WP_033631415.1 NZ_CP100765:55775-56035 [Serratia nematodiphila]
MNTKVITAHVPLPLAEKVDEMAAKLERSRGWIVKQALTAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086G6D5

Antitoxin

Source ID Structure
AlphaFold DB A0A086G6D4

References