Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4390789..4391458 Replicon chromosome
Accession NZ_CP100764
Organism Serratia plymuthica strain SASK2000

Toxin (Protein)


Gene name cptA Uniprot ID A0A7U3Z5B1
Locus tag NLX81_RS20890 Protein ID WP_013814381.1
Coordinates 4390789..4391211 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S4YS10
Locus tag NLX81_RS20895 Protein ID WP_004952428.1
Coordinates 4391192..4391458 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX81_RS20870 (NLX81_20870) 4386674..4387192 + 519 WP_004952413.1 flavodoxin FldB -
NLX81_RS20875 (NLX81_20875) 4387230..4388594 - 1365 WP_013814378.1 cell envelope integrity protein CreD -
NLX81_RS20880 (NLX81_20880) 4388679..4390097 - 1419 WP_013814379.1 two-component system sensor histidine kinase CreC -
NLX81_RS20885 (NLX81_20885) 4390094..4390789 - 696 WP_013814380.1 two-component system response regulator CreB -
NLX81_RS20890 (NLX81_20890) 4390789..4391211 - 423 WP_013814381.1 protein YgfX Toxin
NLX81_RS20895 (NLX81_20895) 4391192..4391458 - 267 WP_004952428.1 FAD assembly factor SdhE Antitoxin
NLX81_RS20900 (NLX81_20900) 4391783..4392775 + 993 WP_013814382.1 tRNA-modifying protein YgfZ -
NLX81_RS20905 (NLX81_20905) 4392923..4393600 - 678 WP_004952439.1 hemolysin III family protein -
NLX81_RS20910 (NLX81_20910) 4393791..4394399 + 609 WP_013814383.1 HD domain-containing protein -
NLX81_RS20915 (NLX81_20915) 4394446..4395771 - 1326 WP_013814384.1 MFS transporter -
NLX81_RS20920 (NLX81_20920) 4395768..4396421 - 654 WP_013814385.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16448.47 Da        Isoelectric Point: 10.6049

>T251387 WP_013814381.1 NZ_CP100764:c4391211-4390789 [Serratia plymuthica]
VAQWRCNVRISWRTQLLSLLTHGVLILLILISPWPEGYGPIWLVLLTLVVFECIRSQKRIASRQGELRLLANKRLSWHGQ
EWLLVKQPWMPRYGILLTLQPIQGKKCRRLWLASDSMGKAEWRHLRQLLLHPSADDDEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10446.90 Da        Isoelectric Point: 5.0843

>AT251387 WP_004952428.1 NZ_CP100764:c4391458-4391192 [Serratia plymuthica]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDQLNDTDKALFIRLLESDDPDLFNWLMNHGAPQDSELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U3Z5B1

Antitoxin

Source ID Structure
AlphaFold DB S4YS10

References