Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1646786..1647305 Replicon
Accession NC_015215
Organism Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069

Toxin (Protein)


Gene name relE Uniprot ID F5WVW3
Locus tag SGGBAA2069_RS08210 Protein ID WP_012962242.1
Coordinates 1646786..1647064 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F5WVW4
Locus tag SGGBAA2069_RS08215 Protein ID WP_012962243.1
Coordinates 1647057..1647305 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-80)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11043.84 Da        Isoelectric Point: 9.3104

>T25138 WP_012962242.1 NC_015215:c1647064-1646786 [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MLKIKYHRQFKRDYKLALKRGLKASKLEEVLEILIKGESLPEKYRDHQLVASKYYQNVRECHIQPDWLLIYQIDDDNLIL
NLVRTGSHSDLF

Download         Length: 279 bp

>T25138 NC_015215:c1647064-1646786 [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGCTTAAAATTAAATACCACAGACAGTTTAAAAGGGATTATAAACTAGCTTTAAAACGTGGTTTAAAAGCTTCCAAACT
AGAGGAAGTCTTAGAAATTTTAATAAAGGGTGAAAGTTTACCAGAAAAATATAGAGACCACCAACTAGTGGCAAGTAAAT
ATTATCAAAATGTTAGAGAATGTCATATTCAGCCTGATTGGTTATTAATTTATCAGATTGATGATGATAATTTGATTTTG
AATTTAGTGCGAACGGGTAGTCATTCGGATTTATTTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9204.69 Da        Isoelectric Point: 4.3193

>AT25138 WP_012962243.1 NC_015215:c1647305-1647057 [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MTTITFKVDDEMKKEATELYKSMGLDLSSALRLFIKQSLVTRSIPFVIKADELTPVLDDVVKGVNMSEEFTDVKSLMESL
DA

Download         Length: 249 bp

>AT25138 NC_015215:c1647305-1647057 [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGACTACAATTACATTTAAAGTTGATGATGAAATGAAAAAGGAAGCAACTGAACTTTATAAATCAATGGGGCTAGATTT
ATCTAGTGCATTACGCTTGTTTATAAAGCAATCTCTTGTTACTCGTAGTATTCCTTTTGTTATTAAAGCTGATGAATTAA
CTCCTGTTCTTGATGATGTCGTAAAGGGTGTTAACATGAGTGAAGAATTTACTGATGTTAAAAGTTTGATGGAGAGTTTA
GATGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F5WVW3

Antitoxin

Source ID Structure
AlphaFold DB F5WVW4

References