Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 513264..513835 Replicon chromosome
Accession NZ_CP100764
Organism Serratia plymuthica strain SASK2000

Toxin (Protein)


Gene name relE Uniprot ID A0A7U3YYL5
Locus tag NLX81_RS02445 Protein ID WP_013811308.1
Coordinates 513560..513835 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A086G7I5
Locus tag NLX81_RS02440 Protein ID WP_013811307.1
Coordinates 513264..513551 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX81_RS02415 (NLX81_02415) 508966..510051 - 1086 WP_013811302.1 carbon-phosphorus lyase complex subunit PhnI -
NLX81_RS02420 (NLX81_02420) 510051..510632 - 582 WP_013811303.1 phosphonate C-P lyase system protein PhnH -
NLX81_RS02425 (NLX81_02425) 510636..511079 - 444 WP_013811304.1 phosphonate C-P lyase system protein PhnG -
NLX81_RS02430 (NLX81_02430) 511080..511805 - 726 WP_174270197.1 phosphonate metabolism transcriptional regulator PhnF -
NLX81_RS02435 (NLX81_02435) 512100..513158 + 1059 WP_013811306.1 permease -
NLX81_RS02440 (NLX81_02440) 513264..513551 + 288 WP_013811307.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NLX81_RS02445 (NLX81_02445) 513560..513835 + 276 WP_013811308.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
NLX81_RS02450 (NLX81_02450) 513839..514303 - 465 WP_013811309.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NLX81_RS02455 (NLX81_02455) 514472..516610 - 2139 WP_254754840.1 anaerobic ribonucleoside-triphosphate reductase -
NLX81_RS02460 (NLX81_02460) 516825..517730 - 906 WP_013811311.1 LysR family transcriptional regulator -
NLX81_RS02465 (NLX81_02465) 517835..518359 + 525 WP_013811312.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10712.50 Da        Isoelectric Point: 9.6236

>T251375 WP_013811308.1 NZ_CP100764:513560-513835 [Serratia plymuthica]
MRIEWDNAALRDRERIFEFLYIFNPQAAVQADNEIDKAVKRLLEHPELGKTWHGKARKLLINKASLLLVYIIVDDVIKVF
AIAHQREKFPN

Download         Length: 276 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11032.33 Da        Isoelectric Point: 5.8001

>AT251375 WP_013811307.1 NZ_CP100764:513264-513551 [Serratia plymuthica]
MESRIQFRIEDETKRLAQKAAEAKGTTLSEACRRLAEQMADEQRAAEEHENWLKDKVDAAFSRLHEGNAVYLSQQEVEES
MDAFKAKIRAKYDRK

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U3YYL5

Antitoxin

Source ID Structure
AlphaFold DB A0A086G7I5

References