Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 57304..57839 Replicon chromosome
Accession NZ_CP100764
Organism Serratia plymuthica strain SASK2000

Toxin (Protein)


Gene name relE Uniprot ID A0A7U3YXN3
Locus tag NLX81_RS00255 Protein ID WP_013810970.1
Coordinates 57564..57839 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U3YXM9
Locus tag NLX81_RS00250 Protein ID WP_013810969.1
Coordinates 57304..57564 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX81_RS00230 (NLX81_00230) 52638..53279 + 642 WP_013810965.1 DcrB-related protein -
NLX81_RS00235 (NLX81_00235) 53315..53920 + 606 WP_013810966.1 glutathione S-transferase -
NLX81_RS00240 (NLX81_00240) 53991..55382 + 1392 WP_013810967.1 L-seryl-tRNA(Sec) selenium transferase -
NLX81_RS00245 (NLX81_00245) 55379..57220 + 1842 WP_013810968.1 selenocysteine-specific translation elongation factor -
NLX81_RS00250 (NLX81_00250) 57304..57564 + 261 WP_013810969.1 ribbon-helix-helix domain-containing protein Antitoxin
NLX81_RS00255 (NLX81_00255) 57564..57839 + 276 WP_013810970.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLX81_RS00260 (NLX81_00260) 57901..59148 - 1248 WP_013810971.1 MFS transporter -
NLX81_RS00265 (NLX81_00265) 59368..60360 + 993 WP_254754798.1 acyltransferase -
NLX81_RS00270 (NLX81_00270) 60355..61278 - 924 WP_013810973.1 DJ-1/PfpI family protein -
NLX81_RS00275 (NLX81_00275) 61278..61832 - 555 WP_013810974.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10684.39 Da        Isoelectric Point: 10.0332

>T251374 WP_013810970.1 NZ_CP100764:57564-57839 [Serratia plymuthica]
MELKWTSKALSDLARLFDFLAPVNRTAAANTIQALVAAPKVLRDNPRIGEKLDEFMPQEVRRILVGHYEMRYQLQSSTIY
VLRIWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9769.17 Da        Isoelectric Point: 4.8430

>AT251374 WP_013810969.1 NZ_CP100764:57304-57564 [Serratia plymuthica]
MNTKVITAHVPLPLADKVDEMAAKLERSRGWIIKQALAAWLDQEEERRRLTLEALADVEQQNIIDHESVETWAVSLSSDK
PLPVPR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U3YXN3

Antitoxin

Source ID Structure
AlphaFold DB A0A7U3YXM9

References