251373

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-mazE/MazE(antitoxin)
Location 3844106..3844703 Replicon chromosome
Accession NZ_CP100755
Organism Alcaligenes sp. NLF5-7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MID00_RS17745 Protein ID WP_115633685.1
Coordinates 3844106..3844381 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag MID00_RS17750 Protein ID WP_254499222.1
Coordinates 3844485..3844703 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MID00_RS17715 (MID00_17715) 3839210..3840118 - 909 WP_254499217.1 hypothetical protein -
MID00_RS17720 (MID00_17720) 3840126..3840725 - 600 WP_254499218.1 hypothetical protein -
MID00_RS17725 (MID00_17725) 3840749..3841498 - 750 WP_254499219.1 DsbC family protein -
MID00_RS17730 (MID00_17730) 3841520..3842008 - 489 WP_254499220.1 PH domain-containing protein -
MID00_RS17735 (MID00_17735) 3842101..3842907 - 807 WP_254499221.1 SprT-like domain-containing protein -
MID00_RS17740 (MID00_17740) 3843840..3844106 + 267 WP_115633686.1 ribbon-helix-helix domain-containing protein -
MID00_RS17745 (MID00_17745) 3844106..3844381 + 276 WP_115633685.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MID00_RS17750 (MID00_17750) 3844485..3844703 + 219 WP_254499222.1 DUF3018 family protein Antitoxin
MID00_RS17755 (MID00_17755) 3845246..3848479 + 3234 WP_254499223.1 helicase-related protein -
MID00_RS17760 (MID00_17760) 3848476..3849282 + 807 WP_254499224.1 DUF4391 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element sul1 / qacE / aadA2 / tet(C) - 3703376..3900507 197131


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Antitoxin MazE-like

(6-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10851.71 Da        Isoelectric Point: 10.3092

>T251373 WP_115633685.1 NZ_CP100755:3844106-3844381 [Alcaligenes sp. NLF5-7]
MKLKWTSKALSDLERLYEFLAVVNKPAAARAVQKLTKAPSILLSNPRIGEQLFMFEPREVRRILVGEYEIRYELQDSFIY
VLRIWHTRENR

Download         Length: 276 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8085.47 Da        Isoelectric Point: 10.1162

>AT251373 WP_254499222.1 NZ_CP100755:3844485-3844703 [Alcaligenes sp. NLF5-7]
MANVHARVQKKCVLLRRAGLRPVQLWVPDTRQPSFAKVCFLQAQIAAKADKVDVGTEHLMDKALADLNSWTE

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References