Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3047056..3047581 Replicon chromosome
Accession NZ_CP100753
Organism Serratia marcescens strain SASK1000

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NLX77_RS14695 Protein ID WP_015377296.1
Coordinates 3047297..3047581 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8B4GIN1
Locus tag NLX77_RS14690 Protein ID WP_004928423.1
Coordinates 3047056..3047307 (+) Length 84 a.a.

Genomic Context


NLX77_RS14660NLX77_RS14665NLX77_RS14670NLX77_RS14675NLX77_RS14680NLX77_RS14685NLX77_RS14690NLX77_RS14695NLX77_RS14700NLX77_RS14705NLX77_RS14710NLX77_RS14715NLX77_RS14720
Location: 3042330..3042872 (543 bp)
Type: Others
Protein ID: WP_015377301.1
Location: 3043135..3043863 (729 bp)
Type: Others
Protein ID: WP_004928406.1
Location: 3043896..3044627 (732 bp)
Type: Others
Protein ID: WP_004928409.1
Location: 3044637..3045353 (717 bp)
Type: Others
Protein ID: WP_004928413.1
Location: 3045353..3046021 (669 bp)
Type: Others
Protein ID: WP_015377298.1
Location: 3046220..3046954 (735 bp)
Type: Others
Protein ID: WP_015377297.1
Location: 3047056..3047307 (252 bp)
Type: Antitoxin
Protein ID: WP_004928423.1
Location: 3047297..3047581 (285 bp)
Type: Toxin
Protein ID: WP_015377296.1
Location: 3047578..3048705 (1128 bp)
Type: Others
Protein ID: WP_118892261.1
Location: 3048775..3049254 (480 bp)
Type: Others
Protein ID: WP_015377294.1
Location: 3049359..3050204 (846 bp)
Type: Others
Protein ID: WP_254519784.1
Location: 3050201..3051163 (963 bp)
Type: Others
Protein ID: WP_021504359.1
Location: 3051188..3052321 (1134 bp)
Type: Others
Protein ID: WP_049187444.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NLX77_RS14660 (NLX77_14660)3042330..3042872+543WP_015377301.1lipoprotein-
NLX77_RS14665 (NLX77_14665)3043135..3043863+729WP_004928406.1arginine ABC transporter ATP-binding protein ArtP-
NLX77_RS14670 (NLX77_14670)3043896..3044627+732WP_004928409.1arginine ABC transporter substrate-binding protein-
NLX77_RS14675 (NLX77_14675)3044637..3045353+717WP_004928413.1arginine ABC transporter permease ArtQ-
NLX77_RS14680 (NLX77_14680)3045353..3046021+669WP_015377298.1arginine ABC transporter permease ArtM-
NLX77_RS14685 (NLX77_14685)3046220..3046954+735WP_015377297.1arginine ABC transporter substrate-binding protein-
NLX77_RS14690 (NLX77_14690)3047056..3047307+252WP_004928423.1prevent-host-death proteinAntitoxin
NLX77_RS14695 (NLX77_14695)3047297..3047581+285WP_015377296.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NLX77_RS14700 (NLX77_14700)3047578..3048705-1128WP_118892261.123S rRNA (uracil(747)-C(5))-methyltransferase RlmC-
NLX77_RS14705 (NLX77_14705)3048775..3049254-480WP_015377294.1YbjO family protein-
NLX77_RS14710 (NLX77_14710)3049359..3050204-846WP_254519784.1putrescine ABC transporter permease PotI-
NLX77_RS14715 (NLX77_14715)3050201..3051163-963WP_021504359.1putrescine ABC transporter permease PotH-
NLX77_RS14720 (NLX77_14720)3051188..3052321-1134WP_049187444.1putrescine ABC transporter ATP-binding subunit PotG-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-83)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 95 a.a.        Molecular weight: 10803.94 Da        Isoelectric Point: 10.6941

>T251365 WP_015377296.1 NZ_CP100753:3047297-3047581 [Serratia marcescens]
MTYKLEFEEHALKEFKKLSPVIREQFKKKLASVLVNPHIPANKLAGLPDCYKIKLRASGFRLVYRVMETEIVVLVLSVGK
RERSAAYTAAKKRL

Download         Length: 285 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9108.39 Da        Isoelectric Point: 4.5203

>AT251365 WP_004928423.1 NZ_CP100753:3047056-3047307 [Serratia marcescens]
MTVQPILADSAVSISDFKKSPNAALKEAQGQPVAVLTNGKISGYYVSPETWEAIAEYLEDIELAEIVRSRMNGKRIKVNL
DDL

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A8B4GIN1

References