Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 891239..891895 Replicon chromosome
Accession NZ_CP100753
Organism Serratia marcescens strain SASK1000

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NLX77_RS04225 Protein ID WP_021504433.1
Coordinates 891506..891895 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NLX77_RS04220 Protein ID WP_254520151.1
Coordinates 891239..891502 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX77_RS04200 (NLX77_04200) 886277..887491 - 1215 WP_015378743.1 D-galactonate dehydratase family protein -
NLX77_RS04205 (NLX77_04205) 887660..888565 - 906 WP_015378742.1 lipid kinase YegS -
NLX77_RS04210 (NLX77_04210) 889032..890384 - 1353 WP_004941558.1 tRNA 5-hydroxyuridine modification protein YegQ -
NLX77_RS04215 (NLX77_04215) 890563..890901 - 339 WP_004941561.1 YegP family protein -
NLX77_RS04220 (NLX77_04220) 891239..891502 + 264 WP_254520151.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NLX77_RS04225 (NLX77_04225) 891506..891895 + 390 WP_021504433.1 type II toxin-antitoxin system VapC family toxin Toxin
NLX77_RS04230 (NLX77_04230) 891903..892619 - 717 WP_015378739.1 two-component system response regulator BaeR -
NLX77_RS04235 (NLX77_04235) 892619..894001 - 1383 WP_254520152.1 two-component system sensor histidine kinase BaeS -
NLX77_RS04240 (NLX77_04240) 893998..895428 - 1431 WP_103086182.1 multidrug transporter subunit MdtD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14398.63 Da        Isoelectric Point: 8.4983

>T251358 WP_021504433.1 NZ_CP100753:891506-891895 [Serratia marcescens]
MYMFDTNTVSHLFRQHPQVLNVMEKLPPSAVCISSVTEAELRYGVAKRRNKALQSMVEAFLAAVTVYAWDSEAARCYGEM
RANMERKGKIMGAMDQLIAAHAQSRGATLVTNDRAFAMVPGLAVEDWTR

Download         Length: 390 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10048.29 Da        Isoelectric Point: 4.6702

>AT251358 WP_254520151.1 NZ_CP100753:891239-891502 [Serratia marcescens]
MERIAKLFKNGRNQAVRVPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLSIIAQTPVPQEFLGAEDRQQGVADR
DPFSEEE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References