Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 521750..522419 Replicon chromosome
Accession NZ_CP100753
Organism Serratia marcescens strain SASK1000

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NLX77_RS02485 Protein ID WP_004931681.1
Coordinates 521997..522419 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag NLX77_RS02480 Protein ID WP_004931679.1
Coordinates 521750..522016 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX77_RS02455 (NLX77_02455) 517317..518243 + 927 WP_015378971.1 ribokinase -
NLX77_RS02460 (NLX77_02460) 518284..518892 - 609 WP_004931670.1 HD domain-containing protein -
NLX77_RS02465 (NLX77_02465) 519076..519750 + 675 WP_021505704.1 hemolysin III family protein -
NLX77_RS02470 (NLX77_02470) 519901..520398 + 498 WP_044030541.1 DUF2165 domain-containing protein -
NLX77_RS02475 (NLX77_02475) 520437..521429 - 993 WP_044030542.1 tRNA-modifying protein YgfZ -
NLX77_RS02480 (NLX77_02480) 521750..522016 + 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
NLX77_RS02485 (NLX77_02485) 521997..522419 + 423 WP_004931681.1 protein YgfX Toxin
NLX77_RS02490 (NLX77_02490) 522485..523003 - 519 WP_004931683.1 flavodoxin FldB -
NLX77_RS02495 (NLX77_02495) 523110..524009 + 900 WP_004931685.1 site-specific tyrosine recombinase XerD -
NLX77_RS02500 (NLX77_02500) 524036..524752 + 717 WP_254520105.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NLX77_RS02505 (NLX77_02505) 524759..526492 + 1734 WP_015378966.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16487.59 Da        Isoelectric Point: 11.0198

>T251356 WP_004931681.1 NZ_CP100753:521997-522419 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGDGEQG

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT251356 WP_004931679.1 NZ_CP100753:521750-522016 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References