251347

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3986703..3987406 Replicon chromosome
Accession NZ_CP100747
Organism Salmonella enterica subsp. enterica serovar Montevideo strain R17.4849

Toxin (Protein)


Gene name ypjF Uniprot ID A0A3V9YEG3
Locus tag NL707_RS19490 Protein ID WP_000854678.1
Coordinates 3986703..3987044 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID A0A3V3HFF7
Locus tag NL707_RS19495 Protein ID WP_000842921.1
Coordinates 3987065..3987406 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL707_RS19475 (3982967) 3982967..3983683 + 717 WP_000532939.1 YebC/PmpR family DNA-binding transcriptional regulator -
NL707_RS19480 (3984161) 3984161..3985036 - 876 WP_000199876.1 HNH endonuclease -
NL707_RS19485 (3985437) 3985437..3986426 - 990 WP_077905735.1 restriction endonuclease -
NL707_RS19490 (3986703) 3986703..3987044 - 342 WP_000854678.1 TA system toxin CbtA family protein Toxin
NL707_RS19495 (3987065) 3987065..3987406 - 342 WP_000842921.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NL707_RS19500 (3987774) 3987774..3990227 + 2454 WP_000985297.1 type I restriction-modification system subunit M -
NL707_RS19505 (3990242) 3990242..3991603 + 1362 WP_001043545.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3978155..4002698 24543


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-112)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12780.67 Da        Isoelectric Point: 6.4593

>T251347 WP_000854678.1 NZ_CP100747:c3987044-3986703 [Salmonella enterica subsp. enterica serovar Montevideo]
MKTLPATTPQAATLCLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNYLVEKYELVRIDRRGF
DWQEQSPYLRAVDILRARQATGLLKRNRISAAQ

Download         Length: 342 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12882.63 Da        Isoelectric Point: 6.6253

>AT251347 WP_000842921.1 NZ_CP100747:c3987406-3987065 [Salmonella enterica subsp. enterica serovar Montevideo]
MKSTDSENDLFLKWGLNRNVTPCFGARLVQEGNRLHYLADRASITGKFINAEYLKLDEIFPHFISQMESMLTTGEMNPRH
AHCVTLYHNGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V9YEG3

Antitoxin

Source ID Structure
AlphaFold DB A0A3V3HFF7

References