Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 849475..850135 Replicon chromosome
Accession NZ_CP100747
Organism Salmonella enterica subsp. enterica serovar Montevideo strain R17.4849

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag NL707_RS04125 Protein ID WP_000244755.1
Coordinates 849722..850135 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NL707_RS04120 Protein ID WP_000351186.1
Coordinates 849475..849741 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL707_RS04100 (845403) 845403..846836 - 1434 WP_001230152.1 6-phospho-beta-glucosidase BglA -
NL707_RS04105 (846995) 846995..847306 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NL707_RS04110 (847470) 847470..848129 + 660 WP_000250289.1 hemolysin III family protein -
NL707_RS04115 (848245) 848245..849225 - 981 WP_000874169.1 tRNA-modifying protein YgfZ -
NL707_RS04120 (849475) 849475..849741 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NL707_RS04125 (849722) 849722..850135 + 414 WP_000244755.1 protein YgfX Toxin
NL707_RS04130 (850188) 850188..850709 - 522 WP_001055885.1 flavodoxin FldB -
NL707_RS04135 (850822) 850822..851718 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NL707_RS04140 (851742) 851742..852455 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NL707_RS04145 (852461) 852461..854194 + 1734 WP_000813393.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T251340 WP_000244755.1 NZ_CP100747:849722-850135 [Salmonella enterica subsp. enterica serovar Montevideo]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT251340 WP_000351186.1 NZ_CP100747:849475-849741 [Salmonella enterica subsp. enterica serovar Montevideo]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References