Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 855534..856194 Replicon chromosome
Accession NZ_CP100744
Organism Salmonella enterica subsp. enterica serovar Newport strain R18.0234

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag FGU68_RS04160 Protein ID WP_000244756.1
Coordinates 855781..856194 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag FGU68_RS04155 Protein ID WP_000351186.1
Coordinates 855534..855800 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGU68_RS04135 (851466) 851466..852899 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
FGU68_RS04140 (853054) 853054..853368 + 315 WP_001182980.1 N(4)-acetylcytidine aminohydrolase -
FGU68_RS04145 (853529) 853529..854188 + 660 WP_000250289.1 hemolysin III family protein -
FGU68_RS04150 (854304) 854304..855284 - 981 WP_000874176.1 tRNA-modifying protein YgfZ -
FGU68_RS04155 (855534) 855534..855800 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
FGU68_RS04160 (855781) 855781..856194 + 414 WP_000244756.1 protein YgfX Toxin
FGU68_RS04165 (856247) 856247..856768 - 522 WP_001055885.1 flavodoxin FldB -
FGU68_RS04170 (856881) 856881..857777 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
FGU68_RS04175 (857801) 857801..858514 + 714 WP_000745621.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FGU68_RS04180 (858520) 858520..860253 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T251323 WP_000244756.1 NZ_CP100744:855781-856194 [Salmonella enterica subsp. enterica serovar Newport]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT251323 WP_000351186.1 NZ_CP100744:855534-855800 [Salmonella enterica subsp. enterica serovar Newport]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References