Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 4002199..4002728 Replicon chromosome
Accession NC_015064
Organism Granulicella tundricola MP5ACTX9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ACIX9_RS17430 Protein ID WP_013581813.1
Coordinates 4002199..4002471 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag ACIX9_RS17435 Protein ID WP_013581814.1
Coordinates 4002474..4002728 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACIX9_RS17405 3997723..3998514 + 792 WP_013581808.1 TIGR03435 family protein -
ACIX9_RS17410 3998524..3999075 - 552 WP_013581809.1 GNAT family N-acetyltransferase -
ACIX9_RS17415 3999065..3999646 - 582 WP_049789376.1 thiamine phosphate synthase -
ACIX9_RS17420 3999798..4001207 + 1410 WP_013581811.1 Si-specific NAD(P)(+) transhydrogenase -
ACIX9_RS17425 4001278..4002195 + 918 WP_013581812.1 ROK family protein -
ACIX9_RS17430 4002199..4002471 - 273 WP_013581813.1 type II toxin-antitoxin system YafQ family toxin Toxin
ACIX9_RS17435 4002474..4002728 - 255 WP_013581814.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ACIX9_RS17440 4002756..4003565 - 810 WP_013581815.1 bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase -
ACIX9_RS17445 4003558..4003818 - 261 WP_013581816.1 hypothetical protein -
ACIX9_RS17450 4003930..4005291 + 1362 WP_013581817.1 adenylosuccinate synthase -
ACIX9_RS17455 4005288..4006244 + 957 WP_013581818.1 aspartate carbamoyltransferase catalytic subunit -
ACIX9_RS17460 4006306..4007607 + 1302 WP_013581819.1 dihydroorotase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-81)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10760.63 Da        Isoelectric Point: 8.1080

>T25117 WP_013581813.1 NC_015064:c4002471-4002199 [Granulicella tundricola MP5ACTX9]
MLEVVMATRFRRDTKLMERRGLKMTKLREVIMLLAQEIELPVRYHDHLLSGSWKDHRECHVEPDWLLIYQLQEGQILFAR
TGTHADLFAK

Download         Length: 273 bp

>T25117 NC_015064:c4002471-4002199 [Granulicella tundricola MP5ACTX9]
ATGCTCGAAGTCGTTATGGCCACCAGATTTCGTCGTGATACGAAGCTCATGGAGCGCCGGGGCCTGAAGATGACCAAGCT
GCGAGAGGTCATCATGCTCCTTGCCCAGGAGATTGAACTGCCCGTGCGATATCACGATCATCTCCTCAGCGGCAGCTGGA
AAGATCATCGCGAATGCCACGTTGAGCCTGACTGGCTTCTGATCTATCAACTGCAGGAAGGCCAAATCCTTTTCGCGCGA
ACCGGAACCCATGCAGATCTTTTCGCAAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8900.22 Da        Isoelectric Point: 3.9649

>AT25117 WP_013581814.1 NC_015064:c4002728-4002474 [Granulicella tundricola MP5ACTX9]
MATTALVVTMDESLDREASAVLAGIGFTVDQAVKLLLTQVVKEKCLPPSLHVPNQDTIDAMQELKDGGGEQFANVEDMLA
SLGI

Download         Length: 255 bp

>AT25117 NC_015064:c4002728-4002474 [Granulicella tundricola MP5ACTX9]
ATGGCCACGACAGCATTAGTCGTCACAATGGATGAAAGCCTTGATCGTGAAGCATCGGCTGTTCTGGCTGGTATCGGCTT
CACCGTCGACCAGGCCGTGAAGCTGTTGCTGACTCAAGTCGTCAAAGAGAAGTGCCTGCCTCCGTCGCTGCACGTTCCTA
ACCAGGACACCATCGACGCGATGCAGGAACTGAAAGACGGTGGCGGCGAGCAGTTTGCCAACGTTGAAGACATGCTGGCC
AGCCTGGGCATTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References