Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2027596..2027741 Replicon chromosome
Accession NZ_CP100710
Organism Salmonella enterica subsp. enterica serovar Blockley strain R18.0186

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2027636..2027739 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2027596..2027741 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL733_RS09710 2024022..2024720 - 699 WP_064047430.1 exodeoxyribonuclease X -
NL733_RS09715 2024744..2025400 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
NL733_RS09720 2025508..2025738 - 231 WP_000856224.1 DNA polymerase III subunit theta -
NL733_RS09725 2025876..2026250 + 375 WP_064047429.1 CopC domain-containing protein YobA -
NL733_RS09730 2026251..2027126 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
NL733_RS09735 2027143..2027496 + 354 WP_000722368.1 YebY family protein -
- 2027596..2027741 - 146 - - Antitoxin
- 2027636..2027739 + 104 - - Toxin
NL733_RS09740 2027870..2028793 - 924 Protein_1903 tyrosine-type recombinase/integrase -
NL733_RS09745 2029057..2029518 - 462 Protein_1904 DNA breaking-rejoining protein -
NL733_RS09750 2029507..2029698 + 192 Protein_1905 glycoside hydrolase family 19 protein -
NL733_RS09755 2029752..2030285 + 534 WP_064047437.1 DUF2514 domain-containing protein -
NL733_RS09760 2030542..2030709 - 168 WP_000789530.1 lytic enzyme -
NL733_RS09765 2030774..2030965 - 192 WP_064047438.1 hypothetical protein -
NL733_RS09770 2031020..2031511 + 492 WP_000348543.1 DUF1441 family protein -
NL733_RS09775 2031498..2032065 + 568 Protein_1910 phage terminase large subunit family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2005726..2069471 63745
- inside Prophage - sopE2 2021934..2056545 34611


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T251159 NZ_CP100710:2027636-2027739 [Salmonella enterica subsp. enterica serovar Blockley]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT251159 NZ_CP100710:c2027741-2027596 [Salmonella enterica subsp. enterica serovar Blockley]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References