251069

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 2392797..2393319 Replicon chromosome
Accession NZ_CP100695
Organism Salmonella enterica subsp. enterica serovar Weltevreden strain R18.0830

Toxin (Protein)


Gene name stbE Uniprot ID B5F5Y5
Locus tag NL711_RS11820 Protein ID WP_000221343.1
Coordinates 2392797..2393081 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A5X3FYG4
Locus tag NL711_RS11825 Protein ID WP_000885426.1
Coordinates 2393071..2393319 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL711_RS11795 (2388357) 2388357..2389598 - 1242 WP_001095731.1 MFS transporter -
NL711_RS11800 (2389588) 2389588..2391096 - 1509 WP_000199407.1 FAD-dependent oxidoreductase -
NL711_RS11805 (2391141) 2391141..2391629 + 489 WP_001293634.1 MarR family winged helix-turn-helix transcriptional regulator -
NL711_RS11810 (2391822) 2391822..2392469 + 648 Protein_2312 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
NL711_RS11815 (2392465) 2392465..2392626 - 162 Protein_2313 RidA family protein -
NL711_RS11820 (2392797) 2392797..2393081 - 285 WP_000221343.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NL711_RS11825 (2393071) 2393071..2393319 - 249 WP_000885426.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NL711_RS11830 (2393471) 2393471..2393590 + 120 Protein_2316 type II and III secretion system -
NL711_RS11835 (2393676) 2393676..2394008 + 333 WP_000253078.1 DUF1493 family protein -
NL711_RS11840 (2394297) 2394297..2394578 - 282 WP_000742000.1 hypothetical protein -
NL711_RS11845 (2394880) 2394880..2396346 - 1467 WP_000987828.1 hypothetical protein -
NL711_RS11850 (2396604) 2396604..2397611 + 1008 WP_000201070.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11075.85 Da        Isoelectric Point: 10.6500

>T251069 WP_000221343.1 NZ_CP100695:c2393081-2392797 [Salmonella enterica subsp. enterica serovar Weltevreden]
MTYKLAFNESALKEWKKLGHTIQEQFKKKLRERLENPRVPASQLHGRKDQYKIKLRGAGYRLVYSVEDEIITVTVIGVGK
RENDAVYKMTRHRS

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9104.35 Da        Isoelectric Point: 3.9947

>AT251069 WP_000885426.1 NZ_CP100695:c2393319-2393071 [Salmonella enterica subsp. enterica serovar Weltevreden]
MAFQILTTTAASITELKRDPMGTFNAGEGAPVAILNRNEPAFYCVPPALYAHLMDILEDEELGRIIDERANERVIEVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5H5JSW4

Antitoxin

Source ID Structure
AlphaFold DB A0A5X3FYG4

References