Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 848015..848675 Replicon chromosome
Accession NZ_CP100695
Organism Salmonella enterica subsp. enterica serovar Weltevreden strain R18.0830

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag NL711_RS04175 Protein ID WP_000244756.1
Coordinates 848262..848675 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NL711_RS04170 Protein ID WP_000351186.1
Coordinates 848015..848281 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL711_RS04150 (843952) 843952..845385 - 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -
NL711_RS04155 (845535) 845535..845846 + 312 WP_001182978.1 N(4)-acetylcytidine aminohydrolase -
NL711_RS04160 (846010) 846010..846669 + 660 WP_000250289.1 hemolysin III family protein -
NL711_RS04165 (846785) 846785..847765 - 981 WP_000874178.1 tRNA-modifying protein YgfZ -
NL711_RS04170 (848015) 848015..848281 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NL711_RS04175 (848262) 848262..848675 + 414 WP_000244756.1 protein YgfX Toxin
NL711_RS04180 (848728) 848728..849249 - 522 WP_001055885.1 flavodoxin FldB -
NL711_RS04185 (849362) 849362..850258 + 897 WP_000434300.1 site-specific tyrosine recombinase XerD -
NL711_RS04190 (850282) 850282..850995 + 714 WP_000745616.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NL711_RS04195 (851001) 851001..852734 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T251067 WP_000244756.1 NZ_CP100695:848262-848675 [Salmonella enterica subsp. enterica serovar Weltevreden]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT251067 WP_000351186.1 NZ_CP100695:848015-848281 [Salmonella enterica subsp. enterica serovar Weltevreden]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References