Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1985440..1985583 Replicon chromosome
Accession NZ_CP100693
Organism Salmonella enterica subsp. enterica serovar London strain R18.1595

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1985479..1985581 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1985440..1985583 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL712_RS09485 1981864..1982562 - 699 WP_023255939.1 exodeoxyribonuclease X -
NL712_RS09490 1982586..1983242 - 657 WP_023245437.1 carbon-nitrogen hydrolase family protein -
NL712_RS09495 1983350..1983580 - 231 WP_000856224.1 DNA polymerase III subunit theta -
NL712_RS09500 1983718..1984092 + 375 WP_000168393.1 CopC domain-containing protein YobA -
NL712_RS09505 1984093..1984968 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
NL712_RS09510 1984985..1985338 + 354 WP_000722368.1 YebY family protein -
- 1985440..1985583 - 144 - - Antitoxin
- 1985479..1985581 + 103 - - Toxin
NL712_RS09515 1985721..1986800 - 1080 WP_058107134.1 phage integrase Arm DNA-binding domain-containing protein -
NL712_RS09520 1986833..1987984 - 1152 Protein_1859 PD-(D/E)XK nuclease-like domain-containing protein -
NL712_RS09525 1987973..1988164 + 192 Protein_1860 glycoside hydrolase family 19 protein -
NL712_RS09530 1988218..1988751 + 534 WP_023256014.1 DUF2514 domain-containing protein -
NL712_RS09535 1989008..1989175 - 168 WP_000789530.1 lytic enzyme -
NL712_RS09540 1989240..1989428 - 189 WP_001034748.1 hypothetical protein -
NL712_RS09545 1989483..1989743 + 261 Protein_1864 DUF1441 family protein -
NL712_RS09550 1989745..1989960 + 216 Protein_1865 shikimate transporter -
NL712_RS09555 1989970..1990257 + 288 Protein_1866 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1962253..2005752 43499


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T251053 NZ_CP100693:1985479-1985581 [Salmonella enterica subsp. enterica serovar London]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT251053 NZ_CP100693:c1985583-1985440 [Salmonella enterica subsp. enterica serovar London]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References