Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2020588..2020733 Replicon chromosome
Accession NZ_CP100689
Organism Salmonella enterica subsp. enterica serovar Newport strain R18.0287

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2020628..2020731 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2020588..2020733 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGU70_RS09695 2017014..2017712 - 699 WP_000944285.1 exodeoxyribonuclease X -
FGU70_RS09700 2017736..2018392 - 657 WP_000100254.1 carbon-nitrogen hydrolase family protein -
FGU70_RS09705 2018500..2018730 - 231 WP_000856224.1 DNA polymerase III subunit theta -
FGU70_RS09710 2018868..2019242 + 375 WP_000168395.1 CopC domain-containing protein YobA -
FGU70_RS09715 2019243..2020118 + 876 WP_000979686.1 copper homeostasis membrane protein CopD -
FGU70_RS09720 2020135..2020488 + 354 WP_000722368.1 YebY family protein -
- 2020588..2020733 - 146 - - Antitoxin
- 2020628..2020731 + 104 - - Toxin
FGU70_RS09725 2020861..2021940 - 1080 WP_000087646.1 phage integrase Arm DNA-binding domain-containing protein -
FGU70_RS09730 2021970..2022965 - 996 Protein_1900 PD-(D/E)XK nuclease-like domain-containing protein -
FGU70_RS09735 2023113..2023361 + 249 Protein_1901 glycoside hydrolase family 19 protein -
FGU70_RS09740 2023358..2023892 + 535 Protein_1902 DUF2514 domain-containing protein -
FGU70_RS09745 2024149..2024316 - 168 WP_000789530.1 lytic enzyme -
FGU70_RS09750 2024381..2024569 - 189 WP_001521334.1 hypothetical protein -
FGU70_RS09755 2024624..2024884 + 261 Protein_1905 DUF1441 family protein -
FGU70_RS09760 2025099..2025443 + 345 Protein_1906 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2014926..2060423 45497


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T251022 NZ_CP100689:2020628-2020731 [Salmonella enterica subsp. enterica serovar Newport]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT251022 NZ_CP100689:c2020733-2020588 [Salmonella enterica subsp. enterica serovar Newport]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References