Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 842443..843103 Replicon chromosome
Accession NZ_CP100685
Organism Salmonella enterica subsp. enterica serovar Goldcoast strain R18.1297

Toxin (Protein)


Gene name cptA Uniprot ID A0A3Y0E4E4
Locus tag FC640_RS04060 Protein ID WP_000244757.1
Coordinates 842690..843103 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag FC640_RS04055 Protein ID WP_000351186.1
Coordinates 842443..842709 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FC640_RS04035 (838371) 838371..839804 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
FC640_RS04040 (839963) 839963..840274 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
FC640_RS04045 (840438) 840438..841097 + 660 WP_000250289.1 hemolysin III family protein -
FC640_RS04050 (841213) 841213..842193 - 981 WP_000874176.1 tRNA-modifying protein YgfZ -
FC640_RS04055 (842443) 842443..842709 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
FC640_RS04060 (842690) 842690..843103 + 414 WP_000244757.1 protein YgfX Toxin
FC640_RS04065 (843156) 843156..843677 - 522 WP_001055885.1 flavodoxin FldB -
FC640_RS04070 (843790) 843790..844686 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
FC640_RS04075 (844710) 844710..845423 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FC640_RS04080 (845429) 845429..847162 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16282.29 Da        Isoelectric Point: 11.1741

>T251004 WP_000244757.1 NZ_CP100685:842690-843103 [Salmonella enterica subsp. enterica serovar Goldcoast]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISRQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT251004 WP_000351186.1 NZ_CP100685:842443-842709 [Salmonella enterica subsp. enterica serovar Goldcoast]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Y0E4E4

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References