Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1521554..1522470 Replicon chromosome
Accession NC_015061
Organism Rahnella sp. Y9602

Toxin (Protein)


Gene name - Uniprot ID H8NRM1
Locus tag RAHAQ_RS07040 Protein ID WP_013574722.1
Coordinates 1521554..1522012 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID H2IQN3
Locus tag RAHAQ_RS07045 Protein ID WP_013574723.1
Coordinates 1522009..1522470 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RAHAQ_RS07015 1517180..1518865 + 1686 WP_013574717.1 choline dehydrogenase -
RAHAQ_RS07020 1518956..1519414 + 459 WP_013574718.1 GNAT family N-acetyltransferase -
RAHAQ_RS07025 1519602..1520534 - 933 WP_013574719.1 LysR family transcriptional regulator -
RAHAQ_RS07030 1520636..1521070 + 435 WP_013574720.1 DMT family transporter -
RAHAQ_RS07035 1521074..1521526 + 453 WP_013574721.1 DMT family transporter -
RAHAQ_RS07040 1521554..1522012 - 459 WP_013574722.1 RES family NAD+ phosphorylase Toxin
RAHAQ_RS07045 1522009..1522470 - 462 WP_013574723.1 DUF2384 domain-containing protein Antitoxin
RAHAQ_RS07050 1522821..1523708 + 888 WP_013574724.1 nucleoside-specific channel-forming protein Tsx -
RAHAQ_RS07055 1523895..1525490 + 1596 WP_013574725.1 ABC-F family ATPase -
RAHAQ_RS07060 1525684..1526445 - 762 WP_013574726.1 molybdopterin-synthase adenylyltransferase MoeB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-136)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(34-95)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 16974.55 Da        Isoelectric Point: 4.7091

>T25097 WP_013574722.1 NC_015061:c1522012-1521554 [Rahnella sp. Y9602]
MKLFRIVQTRHLATAWSGAGAQLYGGRWNPPGRPVVYVTTSISLAILEILVHLQNSMLMRSYTLLSIEVPEELLDTLEVS
ELAADWRSASVPDSTQRQGDVWLAEGEYVGLKVPSVIVPSEYNVLLNPLHPAFADLLSSVEREPMMFDPRLQ

Download         Length: 459 bp

>T25097 NC_015061:c1522012-1521554 [Rahnella sp. Y9602]
TTGAAGCTGTTTCGTATCGTGCAGACCCGTCATCTGGCGACAGCCTGGTCGGGAGCCGGCGCGCAACTTTATGGCGGGCG
CTGGAATCCGCCAGGCAGGCCGGTCGTCTATGTCACCACCAGCATCTCACTGGCTATCCTGGAAATTCTGGTGCATTTGC
AAAACAGCATGCTGATGCGTTCCTATACCTTGCTGAGTATTGAGGTGCCAGAGGAACTGCTGGATACGCTGGAAGTTTCA
GAGCTTGCCGCCGACTGGCGAAGCGCATCAGTGCCTGACAGCACTCAACGTCAGGGTGACGTCTGGCTTGCAGAAGGTGA
ATATGTCGGGCTGAAAGTGCCGTCAGTGATTGTGCCGTCGGAATACAACGTATTACTTAATCCGCTACACCCGGCTTTTG
CCGATTTACTGAGTTCAGTAGAACGCGAGCCCATGATGTTTGACCCGCGCCTGCAATAA

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 16505.80 Da        Isoelectric Point: 7.0196

>AT25097 WP_013574723.1 NC_015061:c1522470-1522009 [Rahnella sp. Y9602]
MNSKITGLSSSSVQDSATPLWQSAGLPASSGISLINAIQKGFPVDSISRLNTELGWPKMVLLEIMGINERNYARRKAGNG
LLKSEESERVARLVRIVDAATDLFEGDRVSALEWFTRPAPALDGSRPLELLSSEAGAVEVSRLIGRLQHGVFS

Download         Length: 462 bp

>AT25097 NC_015061:c1522470-1522009 [Rahnella sp. Y9602]
ATGAATTCAAAAATTACCGGGCTGTCTTCCAGCTCTGTGCAAGATTCTGCAACGCCGCTTTGGCAATCTGCGGGCCTTCC
CGCAAGCAGCGGAATCAGTTTGATAAATGCCATACAAAAGGGATTTCCGGTTGATAGTATCAGCCGTCTTAATACTGAGC
TGGGATGGCCAAAAATGGTGTTACTGGAAATCATGGGCATTAACGAACGCAACTATGCCCGGCGTAAAGCCGGGAACGGA
TTGCTAAAAAGTGAAGAGAGTGAACGTGTGGCGCGACTGGTTCGCATCGTGGATGCCGCAACTGATTTGTTCGAAGGGGA
TCGTGTCTCGGCGCTCGAATGGTTCACCCGCCCTGCTCCGGCACTGGATGGTTCACGTCCGCTGGAACTGCTGTCTTCTG
AAGCGGGTGCTGTGGAAGTCAGCCGCCTGATTGGTCGTCTCCAGCACGGTGTTTTCAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB H8NRM1

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3F7Y1

References