Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 822604..823264 Replicon chromosome
Accession NZ_CP100678
Organism Salmonella enterica subsp. enterica serovar Anatum strain R17.0809

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag NL708_RS03975 Protein ID WP_000244756.1
Coordinates 822851..823264 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NL708_RS03970 Protein ID WP_000351186.1
Coordinates 822604..822870 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL708_RS03950 (818533) 818533..819966 - 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -
NL708_RS03955 (820124) 820124..820435 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NL708_RS03960 (820599) 820599..821258 + 660 WP_000250289.1 hemolysin III family protein -
NL708_RS03965 (821374) 821374..822354 - 981 WP_000874178.1 tRNA-modifying protein YgfZ -
NL708_RS03970 (822604) 822604..822870 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NL708_RS03975 (822851) 822851..823264 + 414 WP_000244756.1 protein YgfX Toxin
NL708_RS03980 (823317) 823317..823838 - 522 WP_001055885.1 flavodoxin FldB -
NL708_RS03985 (823951) 823951..824847 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NL708_RS03990 (824871) 824871..825584 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NL708_RS03995 (825590) 825590..827323 + 1734 WP_000813389.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T250967 WP_000244756.1 NZ_CP100678:822851-823264 [Salmonella enterica subsp. enterica serovar Anatum]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT250967 WP_000351186.1 NZ_CP100678:822604-822870 [Salmonella enterica subsp. enterica serovar Anatum]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References