Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3641539..3642199 Replicon chromosome
Accession NZ_CP100670
Organism Salmonella enterica subsp. enterica serovar Mbandaka strain R17.0904

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag NL713_RS17570 Protein ID WP_000244755.1
Coordinates 3641539..3641952 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NL713_RS17575 Protein ID WP_000351186.1
Coordinates 3641933..3642199 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL713_RS17550 (3637480) 3637480..3639213 - 1734 WP_000813392.1 single-stranded-DNA-specific exonuclease RecJ -
NL713_RS17555 (3639219) 3639219..3639932 - 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NL713_RS17560 (3639956) 3639956..3640852 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NL713_RS17565 (3640965) 3640965..3641486 + 522 WP_017441091.1 flavodoxin FldB -
NL713_RS17570 (3641539) 3641539..3641952 - 414 WP_000244755.1 protein YgfX Toxin
NL713_RS17575 (3641933) 3641933..3642199 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NL713_RS17580 (3642449) 3642449..3643429 + 981 WP_017441090.1 tRNA-modifying protein YgfZ -
NL713_RS17585 (3643545) 3643545..3644204 - 660 WP_000250289.1 hemolysin III family protein -
NL713_RS17590 (3644368) 3644368..3644679 - 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NL713_RS17595 (3644837) 3644837..3646270 + 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T250958 WP_000244755.1 NZ_CP100670:c3641952-3641539 [Salmonella enterica subsp. enterica serovar Mbandaka]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT250958 WP_000351186.1 NZ_CP100670:c3642199-3641933 [Salmonella enterica subsp. enterica serovar Mbandaka]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References