Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 803301..803936 | Replicon | chromosome |
| Accession | NC_015061 | ||
| Organism | Rahnella sp. Y9602 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | H8NSH0 |
| Locus tag | RAHAQ_RS25975 | Protein ID | WP_013574084.1 |
| Coordinates | 803754..803936 (-) | Length | 61 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | H8NSG9 |
| Locus tag | RAHAQ_RS03775 | Protein ID | WP_013574083.1 |
| Coordinates | 803301..803732 (-) | Length | 144 a.a. |
Genomic Context
Location: 798510..799964 (1455 bp)
Type: Others
Protein ID: WP_013574078.1
Type: Others
Protein ID: WP_013574078.1
Location: 799988..800509 (522 bp)
Type: Others
Protein ID: WP_013574079.1
Type: Others
Protein ID: WP_013574079.1
Location: 800684..801022 (339 bp)
Type: Others
Protein ID: WP_013574080.1
Type: Others
Protein ID: WP_013574080.1
Location: 801012..801773 (762 bp)
Type: Others
Protein ID: WP_013574081.1
Type: Others
Protein ID: WP_013574081.1
Location: 801948..803132 (1185 bp)
Type: Others
Protein ID: WP_013574082.1
Type: Others
Protein ID: WP_013574082.1
Location: 803301..803732 (432 bp)
Type: Antitoxin
Protein ID: WP_013574083.1
Type: Antitoxin
Protein ID: WP_013574083.1
Location: 803754..803936 (183 bp)
Type: Toxin
Protein ID: WP_013574084.1
Type: Toxin
Protein ID: WP_013574084.1
Location: 804053..805048 (996 bp)
Type: Others
Protein ID: WP_013574085.1
Type: Others
Protein ID: WP_013574085.1
Location: 805073..806083 (1011 bp)
Type: Others
Protein ID: WP_013574086.1
Type: Others
Protein ID: WP_013574086.1
Location: 806189..807388 (1200 bp)
Type: Others
Protein ID: WP_013574087.1
Type: Others
Protein ID: WP_013574087.1
Location: 807385..808581 (1197 bp)
Type: Others
Protein ID: WP_013574088.1
Type: Others
Protein ID: WP_013574088.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RAHAQ_RS03750 | 798510..799964 | - | 1455 | WP_013574078.1 | efflux transporter outer membrane subunit | - |
| RAHAQ_RS03755 | 799988..800509 | - | 522 | WP_013574079.1 | transcriptional repressor MprA | - |
| RAHAQ_RS03760 | 800684..801022 | - | 339 | WP_013574080.1 | L-valine transporter subunit YgaH | - |
| RAHAQ_RS03765 | 801012..801773 | - | 762 | WP_013574081.1 | AzlC family ABC transporter permease | - |
| RAHAQ_RS03770 | 801948..803132 | - | 1185 | WP_013574082.1 | MFS transporter | - |
| RAHAQ_RS03775 | 803301..803732 | - | 432 | WP_013574083.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| RAHAQ_RS25975 | 803754..803936 | - | 183 | WP_013574084.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| RAHAQ_RS03780 | 804053..805048 | - | 996 | WP_013574085.1 | glycine betaine/L-proline ABC transporter substrate-binding protein ProX | - |
| RAHAQ_RS03785 | 805073..806083 | - | 1011 | WP_013574086.1 | glycine betaine/L-proline ABC transporter substrate-binding protein ProX | - |
| RAHAQ_RS03790 | 806189..807388 | - | 1200 | WP_013574087.1 | glycine betaine/L-proline ABC transporter permease ProW | - |
| RAHAQ_RS03795 | 807385..808581 | - | 1197 | WP_013574088.1 | glycine betaine/L-proline ABC transporter ATP-binding protein ProV | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6646.89 Da Isoelectric Point: 11.1595
>T25095 WP_013574084.1 NC_015061:c803936-803754 [Rahnella sp. Y9602]
MKSTELIKALLAAGCELKRHRGGSHQIWWSPVTNKTFPVPHPKNDLPVGTLKSIRKMAGI
MKSTELIKALLAAGCELKRHRGGSHQIWWSPVTNKTFPVPHPKNDLPVGTLKSIRKMAGI
Download Length: 183 bp
>T25095 NC_015061:c803936-803754 [Rahnella sp. Y9602]
ATGAAATCAACGGAATTGATTAAAGCGCTGCTTGCAGCGGGTTGTGAACTCAAGCGTCACCGGGGAGGAAGTCATCAAAT
TTGGTGGTCACCTGTCACCAACAAAACCTTTCCCGTTCCCCACCCCAAAAATGATTTACCTGTGGGAACTCTCAAATCCA
TTAGAAAAATGGCAGGGATATGA
ATGAAATCAACGGAATTGATTAAAGCGCTGCTTGCAGCGGGTTGTGAACTCAAGCGTCACCGGGGAGGAAGTCATCAAAT
TTGGTGGTCACCTGTCACCAACAAAACCTTTCCCGTTCCCCACCCCAAAAATGATTTACCTGTGGGAACTCTCAAATCCA
TTAGAAAAATGGCAGGGATATGA
Antitoxin
Download Length: 144 a.a. Molecular weight: 16317.52 Da Isoelectric Point: 4.4314
>AT25095 WP_013574083.1 NC_015061:c803732-803301 [Rahnella sp. Y9602]
MFFSVGLETPKDDKTAYGMVVPAFTAFDYGCFSAADTREEIAPMVREAILMTVEDLIESERFVVDDIFDAGHLVYAANPE
YADFDTWFLIDIDLSEFEGKAHRINISLPDTLIKRIDNKVKNHPSYRDRSHFLAMAARKELLT
MFFSVGLETPKDDKTAYGMVVPAFTAFDYGCFSAADTREEIAPMVREAILMTVEDLIESERFVVDDIFDAGHLVYAANPE
YADFDTWFLIDIDLSEFEGKAHRINISLPDTLIKRIDNKVKNHPSYRDRSHFLAMAARKELLT
Download Length: 432 bp
>AT25095 NC_015061:c803732-803301 [Rahnella sp. Y9602]
ATGTTCTTTTCAGTCGGTCTTGAAACACCAAAAGATGACAAAACCGCTTACGGTATGGTGGTACCTGCATTTACCGCGTT
TGATTACGGATGCTTCTCTGCAGCGGATACCCGTGAAGAAATCGCCCCTATGGTTCGCGAAGCCATCCTGATGACAGTAG
AAGATTTGATCGAAAGCGAACGCTTTGTTGTTGACGATATTTTTGATGCAGGCCATTTGGTGTATGCCGCTAATCCCGAA
TATGCCGACTTCGATACCTGGTTTTTGATTGATATTGATCTCTCGGAATTCGAAGGGAAAGCGCATCGAATCAATATTTC
GCTGCCTGACACCCTGATCAAACGCATTGATAATAAAGTTAAAAATCATCCGTCATATCGCGACCGCAGCCATTTTCTGG
CGATGGCCGCACGTAAAGAATTGCTGACCTGA
ATGTTCTTTTCAGTCGGTCTTGAAACACCAAAAGATGACAAAACCGCTTACGGTATGGTGGTACCTGCATTTACCGCGTT
TGATTACGGATGCTTCTCTGCAGCGGATACCCGTGAAGAAATCGCCCCTATGGTTCGCGAAGCCATCCTGATGACAGTAG
AAGATTTGATCGAAAGCGAACGCTTTGTTGTTGACGATATTTTTGATGCAGGCCATTTGGTGTATGCCGCTAATCCCGAA
TATGCCGACTTCGATACCTGGTTTTTGATTGATATTGATCTCTCGGAATTCGAAGGGAAAGCGCATCGAATCAATATTTC
GCTGCCTGACACCCTGATCAAACGCATTGATAATAAAGTTAAAAATCATCCGTCATATCGCGACCGCAGCCATTTTCTGG
CGATGGCCGCACGTAAAGAATTGCTGACCTGA