Detailed information of TA system TA250941

Bioinformatically predicted

Overview

TA module

• Type: III
• Classification (family/domain): toxIN/ToxN(toxin)
• Location: 5448..6080
• Replicon: plasmid pR18.1630_6.1k
• Accession: NZ_CP100669
• Organism: Salmonella enterica subsp. enterica serovar Enteritidis strain R18.1630

Toxin (Protein)

• Gene name: toxN
• Uniprot ID: -
• Locus tag: NL709_RS24060
• Protein ID: WP_094198730.1
• Coordinates: 5448..5963 (-)
• Length: 172 a.a.

Antitoxin (RNA)

Gene name	toxI
Locus tag	-
Coordinates	5965..6080 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NL709_RS24020 (1204)	1204..1395	-	192	WP_000165985.1	Rop family plasmid primer RNA-binding protein	-
NL709_RS24025 (1461)	1461..1784	+	324	WP_000955998.1	MobC family plasmid mobilization relaxosome protein	-
NL709_RS24030 (1993)	1993..2424	+	432	Protein_3	relaxase/mobilization nuclease domain-containing protein	-
NL709_RS24035 (2462)	2462..2980	+	519	WP_254534719.1	MbeB family mobilization protein	-
NL709_RS24040 (2987)	2987..3220	+	234	WP_029401705.1	MbeD family mobilization/exclusion protein	-
NL709_RS24045 (3533)	3533..3814	-	282	WP_024177387.1	hypothetical protein	-
NL709_RS24050 (3824)	3824..4081	-	258	WP_001508827.1	hypothetical protein	-
NL709_RS24055 (4644)	4644..5336	+	693	WP_001508828.1	hypothetical protein	-
NL709_RS24060 (5448)	5448..5963	-	516	WP_094198730.1	type III toxin-antitoxin system ToxN/AbiQ family toxin	Toxin
- (6015)	6015..6072	-	58	NuclAT_11	-	-
- (6015)	6015..6072	-	58	NuclAT_11	-	-
- (6015)	6015..6072	-	58	NuclAT_11	-	-
- (6015)	6015..6072	-	58	NuclAT_11	-	-
- (5965)	5965..6080	-	116	NuclAT_4	-	Antitoxin
- (5965)	5965..6080	-	116	NuclAT_4	-	Antitoxin
- (5965)	5965..6080	-	116	NuclAT_4	-	Antitoxin
- (5965)	5965..6080	-	116	NuclAT_4	-	Antitoxin
- (6015)	6015..6080	-	66	NuclAT_10	-	-
- (6015)	6015..6080	-	66	NuclAT_10	-	-
- (6015)	6015..6080	-	66	NuclAT_10	-	-
- (6015)	6015..6080	-	66	NuclAT_10	-	-
- (6015)	6015..6080	-	66	NuclAT_7	-	-
- (6015)	6015..6080	-	66	NuclAT_7	-	-
- (6015)	6015..6080	-	66	NuclAT_7	-	-
- (6015)	6015..6080	-	66	NuclAT_7	-	-
- (6015)	6015..6080	-	66	NuclAT_8	-	-
- (6015)	6015..6080	-	66	NuclAT_8	-	-
- (6015)	6015..6080	-	66	NuclAT_8	-	-
- (6015)	6015..6080	-	66	NuclAT_8	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	-	1..6080	6080

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ToxN/AbiQ toxin (1-160)

Sequences

Toxin

Protein

• Length: 172 a.a.
• Molecular weight: 19862.85 Da
• Isoelectric Point: 6.1125

>T250941 WP_094198730.1 NZ_CP100669:c5963-5448 [Salmonella enterica subsp. enterica serovar Enteritidis]
MKFYTISSSYIKYLKDFDDKVPNSEDPTYNNPKAFIGIVLEIEGHKYLAPLTSPKAWHANVKESSPAFFKLHENGVPDNQ
LGLINLKFMIPIIEAEVSLLDLDSMPDTPYKRMLYKQLQFIRVNEDKISEKSKLLRNLALQGRMQRTCDFAVLEEKYQHF
GKKPEDMEIDD

Nucleotide

• Length: 516 bp

Antitoxin

Nucleotide

• Length: 116 bp

>AT250941 NZ_CP100669:c6080-5965 [Salmonella enterica subsp. enterica serovar Enteritidis]
AGAAATTCAGGTGATTTGCTACCTTTAAGTGCAGCTAGAAATTTAGGTCATTTACTACCTTAAAGTAATAAAGTAAAAAA
GGCGACTATACACAGTCGCCTTTTTTACGAGAAAAA

Structures

Antitoxin