250919

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 5634900..5635506 Replicon chromosome
Accession NZ_CP100660
Organism Pseudomonas fluorescens strain ZL22

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag NLL86_RS26020 Protein ID WP_254485629.1
Coordinates 5635171..5635506 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag NLL86_RS26015 Protein ID WP_254481896.1
Coordinates 5634900..5635148 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLL86_RS25990 (NLL86_25990) 5630268..5630438 + 171 Protein_5097 integrase -
NLL86_RS25995 (NLL86_25995) 5630435..5630827 + 393 WP_254481883.1 hypothetical protein -
NLL86_RS26000 (NLL86_26000) 5630988..5632892 + 1905 WP_254481892.1 AAA family ATPase -
NLL86_RS26005 (NLL86_26005) 5633767..5634219 - 453 WP_254481893.1 DUF2442 domain-containing protein -
NLL86_RS26010 (NLL86_26010) 5634590..5634790 + 201 WP_254481895.1 hypothetical protein -
NLL86_RS26015 (NLL86_26015) 5634900..5635148 + 249 WP_254481896.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NLL86_RS26020 (NLL86_26020) 5635171..5635506 + 336 WP_254485629.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLL86_RS26025 (NLL86_26025) 5635536..5637833 - 2298 WP_254481898.1 TonB-dependent siderophore receptor -
NLL86_RS26030 (NLL86_26030) 5637974..5638693 + 720 WP_254481901.1 response regulator transcription factor -
NLL86_RS26035 (NLL86_26035) 5638695..5640074 + 1380 WP_254481904.1 ATP-binding protein -
NLL86_RS26040 (NLL86_26040) 5640071..5640496 - 426 WP_254481906.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5617594..5635506 17912


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-95)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12690.39 Da        Isoelectric Point: 5.5433

>T250919 WP_254485629.1 NZ_CP100660:5635171-5635506 [Pseudomonas fluorescens]
IIRFTDSASQRIEDQVHHRAVYHGTQTALQKITALVDSIEQRLSAAPVGYPVSPQASDLGVMQYRELNVDGYRVFYEIFE
DDHTIAVELVVRQKQSVEQALIRYCLIYPLP

Download         Length: 336 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9181.52 Da        Isoelectric Point: 8.4580

>AT250919 WP_254481896.1 NZ_CP100660:5634900-5635148 [Pseudomonas fluorescens]
MRVETISYLKRHAADLDLAEPMIVTQNGTPAYVVESYADRKQRDEAIALVKLLAMGSREYAQGKHSSAEDLKARLLKKFS
GE

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References