Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3576909..3577425 Replicon chromosome
Accession NZ_CP100660
Organism Pseudomonas fluorescens strain ZL22

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NLL86_RS16400 Protein ID WP_254480407.1
Coordinates 3576909..3577190 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NLL86_RS16405 Protein ID WP_254480408.1
Coordinates 3577180..3577425 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLL86_RS16380 (NLL86_16380) 3572226..3573248 - 1023 WP_254480403.1 histone deacetylase family protein -
NLL86_RS16385 (NLL86_16385) 3573248..3574489 - 1242 WP_254480404.1 Zn-dependent hydrolase -
NLL86_RS16390 (NLL86_16390) 3574520..3575824 - 1305 WP_254480405.1 MFS transporter -
NLL86_RS16395 (NLL86_16395) 3576004..3576912 + 909 WP_254480406.1 LysR family transcriptional regulator -
NLL86_RS16400 (NLL86_16400) 3576909..3577190 - 282 WP_254480407.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLL86_RS16405 (NLL86_16405) 3577180..3577425 - 246 WP_254480408.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NLL86_RS16410 (NLL86_16410) 3577661..3578203 + 543 WP_254485587.1 WYL domain-containing protein -
NLL86_RS16415 (NLL86_16415) 3578302..3579237 + 936 WP_254480409.1 cyclase family protein -
NLL86_RS16420 (NLL86_16420) 3579249..3580259 - 1011 WP_254480410.1 AraC family transcriptional regulator -
NLL86_RS16425 (NLL86_16425) 3580428..3581612 + 1185 WP_254480411.1 acetyl-CoA C-acyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-74)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10836.66 Da        Isoelectric Point: 10.6500

>T250916 WP_254480407.1 NZ_CP100660:c3577190-3576909 [Pseudomonas fluorescens]
MTYKLEFLPSALKEWGKTGHTVREQLKKKLGERLQSPKVQADALRDMPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
REHGEVYRAAQKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8796.25 Da        Isoelectric Point: 4.4963

>AT250916 WP_254480408.1 NZ_CP100660:c3577425-3577180 [Pseudomonas fluorescens]
MQNIFANVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELSELAKSRMGEKGVPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References