Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1583737..1585406 Replicon chromosome
Accession NZ_CP100660
Organism Pseudomonas fluorescens strain ZL22

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag NLL86_RS07380 Protein ID WP_254483967.1
Coordinates 1584555..1585406 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag NLL86_RS07375 Protein ID WP_254483966.1
Coordinates 1583737..1584558 (-) Length 274 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLL86_RS07355 (NLL86_07355) 1578945..1580435 - 1491 WP_254483954.1 aldehyde dehydrogenase -
NLL86_RS07360 (NLL86_07360) 1580445..1581248 - 804 WP_254483956.1 aspartate dehydrogenase -
NLL86_RS07365 (NLL86_07365) 1581259..1582944 - 1686 WP_254483964.1 thiamine pyrophosphate-binding protein -
NLL86_RS07370 (NLL86_07370) 1582937..1583734 - 798 WP_254483965.1 SDR family oxidoreductase -
NLL86_RS07375 (NLL86_07375) 1583737..1584558 - 822 WP_254483966.1 IclR family transcriptional regulator Antitoxin
NLL86_RS07380 (NLL86_07380) 1584555..1585406 - 852 WP_254483967.1 alpha/beta hydrolase Toxin
NLL86_RS07385 (NLL86_07385) 1585411..1585950 - 540 WP_254483968.1 cupin domain-containing protein -
NLL86_RS07390 (NLL86_07390) 1585967..1586728 - 762 WP_254483969.1 SDR family oxidoreductase -
NLL86_RS07395 (NLL86_07395) 1586728..1587504 - 777 WP_254483977.1 ABC transporter permease -
NLL86_RS07400 (NLL86_07400) 1587532..1588524 - 993 WP_254483979.1 ABC transporter substrate-binding protein -
NLL86_RS07405 (NLL86_07405) 1588554..1589390 - 837 WP_254485537.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(38-155)

Antitoxin

Transcription regulator IclR, N-terminal

(19-69)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 30196.49 Da        Isoelectric Point: 7.8796

>T250915 WP_254483967.1 NZ_CP100660:c1585406-1584555 [Pseudomonas fluorescens]
MPALTDTCVSQLQRQFGERLLPLGDGQQAIREAGNGTAIVLLHGIGSGAASWLQVALGLRQRARVIAWDAPGYGQSAPLP
MASPRAGDYAARLASLLDALALERCVLVGHSLGAMTAAAFTQRHPERVSELVLLSPARGYGARPEQACEVRDKRLHDLAT
LGVERIARMRSANLVSANASDSALAWVRWNMARLQPAGYRQAIELLCGDDLLRYRELQVPCQVHCGSADSITTADDCRAL
AQAFGAPFRLIHGAGHACAIEQPETVTGRLARALDASFTGSVQ

Download         Length: 852 bp

Antitoxin


Download         Length: 274 a.a.        Molecular weight: 30045.41 Da        Isoelectric Point: 6.7576

>AT250915 WP_254483966.1 NZ_CP100660:c1584558-1583737 [Pseudomonas fluorescens]
MNDTDAMKDNQDRYTVPGLERGLLLLCEFSRQNRTLTAPELARRLALPRSTIFRLLSTLETMGFVTRNGNEYRLGMSVLR
LGFEYLASLELTELGQPILARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVTVGTRLPAHATVLGRVLLADLSLA
ELRELYPEEHLERHSPSTPKTVLELFDLVQADRLRGYVHGEGFFESTISTLAAPVRDASGRVAAALGLTIPTAQVGHINF
DSLLGQVRGSADELSRLLDYRPGAGQVTALMRD

Download         Length: 822 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References