Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1378411..1379327 Replicon chromosome
Accession NZ_CP100651
Organism Bacillus halotolerans strain MEC_B334

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag NLW79_RS07130 Protein ID WP_106022239.1
Coordinates 1378581..1379327 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag NLW79_RS07125 Protein ID WP_106022240.1
Coordinates 1378411..1378581 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLW79_RS07090 (1375279) 1375279..1375605 + 327 WP_127695404.1 XkdW family protein -
NLW79_RS07095 (1375602) 1375602..1375766 + 165 WP_015715740.1 XkdX family protein -
NLW79_RS07100 (1375812) 1375812..1376651 + 840 WP_127695402.1 phage-like element PBSX protein XepA -
NLW79_RS07105 (1376704) 1376704..1376973 + 270 WP_106020445.1 hemolysin XhlA family protein -
NLW79_RS07110 (1376985) 1376985..1377248 + 264 WP_024121086.1 phage holin -
NLW79_RS07115 (1377261) 1377261..1378154 + 894 WP_127695400.1 N-acetylmuramoyl-L-alanine amidase -
NLW79_RS07120 (1378190) 1378190..1378327 - 138 WP_125825426.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
NLW79_RS07125 (1378411) 1378411..1378581 - 171 WP_106022240.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
NLW79_RS07130 (1378581) 1378581..1379327 - 747 WP_106022239.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
NLW79_RS07135 (1379437) 1379437..1380438 - 1002 WP_024121092.1 inorganic phosphate transporter -
NLW79_RS07140 (1380451) 1380451..1381068 - 618 WP_010333926.1 DUF47 domain-containing protein -
NLW79_RS07145 (1381344) 1381344..1382660 - 1317 WP_024121093.1 serine/threonine exchanger -
NLW79_RS07150 (1383055) 1383055..1384005 + 951 WP_254518202.1 ring-cleaving dioxygenase -
NLW79_RS07155 (1384165) 1384165..1384245 + 81 Protein_1346 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29048.43 Da        Isoelectric Point: 4.4986

>T250892 WP_106022239.1 NZ_CP100651:c1379327-1378581 [Bacillus halotolerans]
MLLFFQIMVWCTMAALGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMIYWTYDPSSLFTNWERYVIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLDRLKTYQYLLKNEPIHVYYGSIEAYAEGIDKLLKTYADKMNLTASL
CHYSTQSDKDRLTEHMEDPADAQTRLDRKDVYYDQYGKVVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6577.68 Da        Isoelectric Point: 11.1569

>AT250892 WP_106022240.1 NZ_CP100651:c1378581-1378411 [Bacillus halotolerans]
MENAFQNGCHPRAKKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDKYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References