250855

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 27740..28422 Replicon plasmid unnamed
Accession NZ_CP100554
Organism Pseudomonas hydrolytica strain KHPS2

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag NLY38_RS25605 Protein ID WP_254348648.1
Coordinates 28060..28422 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag NLY38_RS25600 Protein ID WP_254348646.1
Coordinates 27740..28063 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLY38_RS25565 (NLY38_25565) 23406..23819 - 414 WP_254348633.1 plasmid mobilization relaxosome protein MobC -
NLY38_RS25570 (NLY38_25570) 24139..24555 + 417 WP_254348634.1 type IV secretory system conjugative DNA transfer family protein -
NLY38_RS25575 (NLY38_25575) 24567..25268 + 702 WP_254348635.1 StbB family protein -
NLY38_RS25580 (NLY38_25580) 25274..25867 + 594 WP_254348637.1 hypothetical protein -
NLY38_RS25585 (NLY38_25585) 25876..26172 + 297 WP_254348640.1 TrbM/KikA/MpfK family conjugal transfer protein -
NLY38_RS25590 (NLY38_25590) 26234..26692 + 459 WP_254348642.1 hypothetical protein -
NLY38_RS25595 (NLY38_25595) 27265..27675 - 411 WP_254348644.1 hypothetical protein -
NLY38_RS25600 (NLY38_25600) 27740..28063 - 324 WP_254348646.1 helix-turn-helix transcriptional regulator Antitoxin
NLY38_RS25605 (NLY38_25605) 28060..28422 - 363 WP_254348648.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLY38_RS25610 (NLY38_25610) 28568..28831 - 264 WP_254348650.1 hypothetical protein -
NLY38_RS25615 (NLY38_25615) 28877..29428 - 552 WP_254348652.1 hypothetical protein -
NLY38_RS25620 (NLY38_25620) 29439..29669 - 231 WP_254348654.1 hypothetical protein -
NLY38_RS25625 (NLY38_25625) 30836..30979 + 144 WP_254348656.1 hypothetical protein -
NLY38_RS25630 (NLY38_25630) 30976..32748 - 1773 WP_254348657.1 DNA cytosine methyltransferase -
NLY38_RS25635 (NLY38_25635) 32745..32975 - 231 WP_254348658.1 hypothetical protein -
NLY38_RS25640 (NLY38_25640) 32989..33390 - 402 WP_254348659.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..83915 83915


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13209.32 Da        Isoelectric Point: 9.9591

>T250855 WP_254348648.1 NZ_CP100554:c28422-28060 [Pseudomonas hydrolytica]
MEKTIKPLFWVGSARKDLQAMPEDVKDTFGFALHLAQLGRKASETKPLKGFGGAGVLEVVESTVSGTYRAVYTVKFGDAV
YVLHCFQKKSTHGIATPKPDMDVINERLKAAEMHAKGERK

Download         Length: 363 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11455.46 Da        Isoelectric Point: 8.5390

>AT250855 WP_254348646.1 NZ_CP100554:c28063-27740 [Pseudomonas hydrolytica]
VIEIECGSGNVFADIGAADPEEMLVKAQLAAKVAEIIEARKLKQAEAAELVGLTQPKLSGVLRGKLRGVSEAKLLDCLRR
LGRDVQIVVGPARRQAEPGRLEVVMAR

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References