Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 3715160..3716571 Replicon chromosome
Accession NZ_CP100551
Organism Pseudomonas sp. KHPS1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NLY39_RS17185 Protein ID WP_096825807.1
Coordinates 3716002..3716571 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NLY39_RS17180 Protein ID WP_003246035.1
Coordinates 3715160..3715999 (-) Length 280 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLY39_RS17165 (NLY39_17165) 3712077..3712982 - 906 WP_096825809.1 GIDE domain-containing protein -
NLY39_RS17170 (NLY39_17170) 3712984..3713556 - 573 WP_003246031.1 LemA family protein -
NLY39_RS17175 (NLY39_17175) 3713747..3715084 + 1338 WP_096825808.1 imelysin family protein -
NLY39_RS17180 (NLY39_17180) 3715160..3715999 - 840 WP_003246035.1 AraC family transcriptional regulator Antitoxin
NLY39_RS17185 (NLY39_17185) 3716002..3716571 - 570 WP_096825807.1 GNAT family protein Toxin
NLY39_RS17190 (NLY39_17190) 3716772..3720260 + 3489 WP_254298330.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
NLY39_RS17195 (NLY39_17195) 3720302..3721120 - 819 WP_254298332.1 MerR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21341.51 Da        Isoelectric Point: 9.8676

>T250851 WP_096825807.1 NZ_CP100551:c3716571-3716002 [Pseudomonas sp. KHPS1]
MFKPQLVTLQRGALRLEPLADADIPALVALAEANRDELLYMSGTQRLDWYRSALAELREQRALPFAIRLGEQLVGTTRFG
DFMNSLPACEIGWTWLDRAQHGSGLNASIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAAREGLLRNHRRLAD
GRLDHTVLYSITDQEWPQVRAALEARFGG

Download         Length: 570 bp

Antitoxin


Download         Length: 280 a.a.        Molecular weight: 30956.10 Da        Isoelectric Point: 7.7422

>AT250851 WP_003246035.1 NZ_CP100551:c3715999-3715160 [Pseudomonas sp. KHPS1]
MQPLTGSERARFSASDDLHGLELLSARFVEHRFAPHVHDGHVIAVLEAGAERYRYRGVDHLAGAGSIALLNPDEVHTGSK
GVEQGWQYRVFYPQPGTFEALLAELESPPAAPPMFHDSVHHDPLLASRLSALHRLLEDPHSEALQRQTLWREAMLELLQR
YARLPAPRGVGQEPRAVALAKELLASQLSEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLRQRRLEQARTLLRSGC
SALSVAMQLGFADQSHLSRQFKQTYGVSPGEYRSAVARG

Download         Length: 840 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References