25085

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 802191..803538 Replicon chromosome
Accession NC_014966
Organism Vibrio vulnificus MO6-24/O

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag VVMO6_RS18275 Protein ID WP_015727856.1
Coordinates 802597..803538 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag VVMO6_RS18270 Protein ID WP_015727855.1
Coordinates 802191..802595 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VVMO6_RS18250 797384..797842 + 459 WP_015727851.1 hypothetical protein -
VVMO6_RS18255 798032..798778 + 747 WP_015727852.1 carbon-nitrogen hydrolase family protein -
VVMO6_RS18260 799277..800041 + 765 WP_015727853.1 nucleotidyltransferase domain-containing protein -
VVMO6_RS18265 800097..801857 - 1761 WP_015727854.1 ABC transporter ATP-binding protein/permease -
VVMO6_RS18270 802191..802595 + 405 WP_015727855.1 hypothetical protein Antitoxin
VVMO6_RS18275 802597..803538 + 942 WP_015727856.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
VVMO6_RS18280 803972..805024 + 1053 WP_015727857.1 MBL fold metallo-hydrolase -
VVMO6_RS18285 805026..806327 + 1302 WP_044024052.1 serine protease -
VVMO6_RS18290 806311..806850 + 540 WP_044024053.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 36057.46 Da        Isoelectric Point: 5.3076

>T25085 WP_015727856.1 NC_014966:802597-803538 [Vibrio vulnificus MO6-24/O]
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKGVRKAWVNEIEQAITHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI

Download         Length: 942 bp

>T25085 NC_014966:802597-803538 [Vibrio vulnificus MO6-24/O]
ATGAACGCACTAAAACAACAATTTCTTGAGGTTTCCGACGCGCTTGAGCTCGGAAACCCTGCCATCATTGAAAAAGATTT
CTGGGTCGTTGCCTTACTTGCCGAGCTAGCAAAAGTTTCTCCTGAATATCATCAAATGGTCTTTTCCGGTGGCACGGCGT
TGGCGAAATCAAACGTTAAAATTCTACGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCAAGCGTTTGATGAA
CTGAGTCGTGCAAAAAAGAAAGGCGTTAGAAAGGCATGGGTTAACGAGATTGAACAGGCGATCACTCATTCAGAACGATT
TACCGTTGAAACGCGATCTGTGCGAGATGAGTACCGTTACGTTGAATTTGAACTCAGATATCCGCAACAGTTTAGTCAAG
TTCCCTGTCTTCGTCCCATCATTAAGTTAGAGTTAATCGAAACCATTCCATTACTGGATGTGGAGTCGCGCAGCATTCAA
TCACTGGTTGCAGAGTTGTACCAACAACCGCACGAAGTGAGTTCATTTGATTGCGTCTCTGTCTATGCCACGTTGGTTGA
AAAAATCATTTCGATGCTGCGCCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTCTAGTTCGCC
ATATCTACGATGTGCATTGCATAACAAAGCTCACAATGTCTGAACTCAACTCGATTGACGGCCTATTCAAAGCGGTCTTG
GAAGAAGATATTGCCCGCTTTGGCAATCAACATGCAGAGTTTGTTGCCAACCCTAAACAAGAGCTACAACTTGGCCTCAA
AGAGCTTGAGGAAAATCCCATTTTCCGCCAACGTTTTCAGGACTTTGTCACACCAATGGTGTTTAACACTGAGCCCCATG
ATTTTGATACCTGCTTTGCCTCATTCAAGCGAATTGCCGCGTCGCTAATTGAAAAAATCTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15129.50 Da        Isoelectric Point: 10.6963

>AT25085 WP_015727855.1 NC_014966:802191-802595 [Vibrio vulnificus MO6-24/O]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTKPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp

>AT25085 NC_014966:802191-802595 [Vibrio vulnificus MO6-24/O]
ATGACAGCAGTAGACCGCATTTGTCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGACGGATT
TGCAAGTTACGACCAAATAGGTCGGGCATTGAGGCAGCTTGTACAGCAAGGGGAGCTAATGAAGCTTGGCTATGGTTTGT
ATACCAAAGCAAGAATCAATAGCCTCACTGGTAAGCCTATGCCTACCAAGCCAGGTGGCACCGATGCTCTTGTGCGTGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAAATGGATAGTCTATCGCAACAAAGTCTTTCAGGTGCGAGTACCCAAATTCC
ATCCTCTGTTCACTATTCATGGAACCCAAAACAGTTTAATCGCAAACTGGTGGTTGGTAGCCGTGTGTTGAACTTGCCAA
GTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References