Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1837620..1837765 Replicon chromosome
Accession NZ_CP100542
Organism Klebsiella pneumoniae strain LH09-d

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1837656..1837758 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1837620..1837765 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ07_RS08955 1832750..1834810 + 2061 WP_004151449.1 oligopeptidase B -
NLZ07_RS08960 1834814..1835473 - 660 WP_021440386.1 exodeoxyribonuclease X -
NLZ07_RS08965 1835552..1835782 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NLZ07_RS08970 1835895..1836269 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NLZ07_RS08975 1836273..1837142 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NLZ07_RS08980 1837159..1837497 + 339 WP_016529031.1 YebY family protein -
- 1837620..1837765 - 146 - - Antitoxin
- 1837656..1837758 + 103 - - Toxin
NLZ07_RS08985 1838134..1838277 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NLZ07_RS08990 1838382..1839350 - 969 WP_004151446.1 VirK/YbjX family protein -
NLZ07_RS08995 1839507..1840160 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
NLZ07_RS09000 1840157..1840348 - 192 WP_002911395.1 YebW family protein -
NLZ07_RS09005 1840446..1840685 - 240 WP_002911393.1 YebV family protein -
NLZ07_RS09010 1840801..1842234 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250812 NZ_CP100542:1837656-1837758 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250812 NZ_CP100542:c1837765-1837620 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References