Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1890272..1890417 Replicon chromosome
Accession NZ_CP100520
Organism Klebsiella pneumoniae strain LH13-d

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1890308..1890410 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1890272..1890417 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ10_RS09190 1885402..1887462 + 2061 WP_004151449.1 oligopeptidase B -
NLZ10_RS09195 1887466..1888125 - 660 WP_002911407.1 exodeoxyribonuclease X -
NLZ10_RS09200 1888204..1888434 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NLZ10_RS09205 1888547..1888921 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NLZ10_RS09210 1888925..1889794 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
NLZ10_RS09215 1889811..1890149 + 339 WP_002911404.1 YebY family protein -
- 1890272..1890417 - 146 - - Antitoxin
- 1890308..1890410 + 103 - - Toxin
NLZ10_RS09220 1890785..1890928 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NLZ10_RS09225 1891033..1892001 - 969 WP_254527536.1 VirK/YbjX family protein -
NLZ10_RS09230 1892158..1892811 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
NLZ10_RS09235 1892808..1892999 - 192 WP_002911395.1 YebW family protein -
NLZ10_RS09240 1893097..1893336 - 240 WP_002911393.1 YebV family protein -
NLZ10_RS09245 1893452..1894885 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250740 NZ_CP100520:1890308-1890410 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250740 NZ_CP100520:c1890417-1890272 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References