Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3431050..3431195 Replicon chromosome
Accession NZ_CP100515
Organism Klebsiella pneumoniae strain LH35-d

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3431057..3431159 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3431050..3431195 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ11_RS16855 (NLZ11_16855) 3426583..3428016 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NLZ11_RS16860 (NLZ11_16860) 3428132..3428371 + 240 WP_002911393.1 YebV family protein -
NLZ11_RS16865 (NLZ11_16865) 3428469..3428660 + 192 WP_002911395.1 YebW family protein -
NLZ11_RS16870 (NLZ11_16870) 3428657..3429310 - 654 WP_020802220.1 protein-serine/threonine phosphatase -
NLZ11_RS16875 (NLZ11_16875) 3429467..3430435 + 969 WP_195770191.1 VirK/YbjX family protein -
NLZ11_RS16880 (NLZ11_16880) 3430540..3430683 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3431050..3431195 + 146 - - Antitoxin
- 3431057..3431159 - 103 - - Toxin
NLZ11_RS16885 (NLZ11_16885) 3431318..3431656 - 339 WP_016529031.1 YebY family protein -
NLZ11_RS16890 (NLZ11_16890) 3431673..3432542 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NLZ11_RS16895 (NLZ11_16895) 3432546..3432920 - 375 WP_004151448.1 CopC domain-containing protein YobA -
NLZ11_RS16900 (NLZ11_16900) 3433033..3433263 + 231 WP_002911406.1 DNA polymerase III subunit theta -
NLZ11_RS16905 (NLZ11_16905) 3433342..3434001 + 660 WP_002911407.1 exodeoxyribonuclease X -
NLZ11_RS16910 (NLZ11_16910) 3434005..3436065 - 2061 WP_159307789.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T250729 NZ_CP100515:c3431159-3431057 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT250729 NZ_CP100515:3431050-3431195 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References